We describe the methodology and application of the polymerase chain reaction to detect
BCR-ABL mRNA as a marker for CML cells. The technique is highly sensitive enabling the …

The polymerase chain reaction (PCR) allows the detection of minimal amounts of nucleic
sequences and has been successfully used to test for the chronic myeloid leukemia-specific …

The prognostic significance of detecting minimal residual disease by polymerase chain
reaction (PCR) amplification of bcr/abl mRNA transcripts was investigated in 27 bone …

We used a modification of the polymerase chain reaction (PCR) to amplify the specific bcr-
abl mRNA from 14 patients with chronic myeloid leukemia (CML) who had previously …

We used the polymerase chain reaction (PCR) to detect residual leukemia-specific mRNA in
blood and marrow from 37 patients in complete hematologic and cytogenetic remission after …

In chronic myeloid leukemia (CML) the polymerase chain reaction (PCR) can be used to
detect minimal residual disease after bone marrow transplantation (BMT). Previous studies …

To evaluate the remission quality of Philadelphia chromosome (Ph)-positive, BCR/ABL-
positive CML patients after allogeneic bone marrow transplantation (BMT) we used the …

Sixteen patients treated by allogeneic bone marrow transplantation (BMT) for chronic
myelogenous leukemia (CML) were evaluated by the polymerase chain reaction (PCR) for …

We have sought to determine whether peripheral blood or bone marrow is more sensitive for
assessment of minimal residual disease in chronic myeloid leukaemia (CML) …

A modified two-step polymerase chain reaction (PCR) was used for the amplification of
BCR/ABL mRNA in 16 patients with Philadelphia chromosomepositive (Ph+) chronic …