[HTML][HTML] Natural product celastrol suppressed macrophage M1 polarization against inflammation in diet-induced obese mice via regulating Nrf2/HO-1, MAP kinase and …

D Luo, Y Guo, Y Cheng, J Zhao, Y Wang… - Aging (Albany NY …, 2017 - ncbi.nlm.nih.gov
Macrophage polarization is implicated in the inflammation in obesity. The aim of the present
study was to examine the anti-inflammatory activities of botanical triterpene celastrol against …

Screening five qi‐tonifying herbs on M2 phenotype macrophages

YX Jiang, Y Chen, Y Yang, XX Chen… - Evidence‐Based …, 2019 - Wiley Online Library
Tumor‐associated macrophages (TAMs) with M2 phenotype play an essential role in tumor
microenvironment (TME) during the progression and development of numerous cancers and …

Macrophage phenotype-switching in cancer

J Zhang, X Zhou, H Hao - European Journal of Pharmacology, 2022 - Elsevier
Tumour-associated macrophages (TAMs) have been found to be of great importance in
tumorigenesis and in promoting malignant progression, including tumour angiogenesis and …

Macrophages as a double-edged weapon: The use of macrophages in cancer immunotherapy and understanding the cross-talk between macrophages and cancer

A Salah, Y Li, H Wang, N Qi, Y Wu - DNA and Cell Biology, 2021 - liebertpub.com
Macrophages (Mϕs) play an essential role in maintaining body homeostasis. They perform
dual functions produced by different subtypes. Mϕs not only fight against pathogens and …

Macrophage polarization in tumour progression

A Sica, P Larghi, A Mancino, L Rubino, C Porta… - Seminars in cancer …, 2008 - Elsevier
Macrophages are a fundamental part of the innate defense mechanisms, which can promote
specific immunity by inducing T cell recruitment and activation. Despite this, their presence …

Anemoside A3 activates TLR4-dependent M1-phenotype macrophage polarization to represses breast tumor growth and angiogenesis

L Yin, Z Fan, P Liu, L Chen, Z Guan, Y Liu… - Toxicology and Applied …, 2021 - Elsevier
The polarization of macrophages has been previously demonstrated to be closely related to
immune and inflammatory processes in the tumorigenesis and progression of breast cancer …

[PDF][PDF] M1 and M2 polarization of macrophages: a mini-review

KY Lee - Med Biol Sci Eng, 2019 - pdfs.semanticscholar.org
The tissue microenvironment regulates differentiation of precursor monocytes into
macrophages. In response to the presence of microbial products, stimulated lymphocytes, or …

[HTML][HTML] Metabolites and Immune Response in Tumor Microenvironments

S Cortellino, VD Longo - Cancers, 2023 - mdpi.com
Simple Summary Cancer cells alter their metabolisms to support growth, thus causing micro-
and macronutrient changes in the metabolite profile that promote an immunosuppressive …

Resveratrol inhibits lung cancer growth by suppressing M2-like polarization of tumor associated macrophages

L Sun, B Chen, R Jiang, J Li, B Wang - Cellular immunology, 2017 - Elsevier
In cancer, tumor associated macrophages (TAMs) play an important role in the cancer
progression, evasion of immunity and dissemination of cancer cells. Inhibition of the …

[HTML][HTML] The role of diet in regulation of macrophages functioning

YR Varaeva, TV Kirichenko, NN Shaposhnikova… - Biomedicines, 2022 - mdpi.com
The great importance of diet for health and high life-expectancy is established. The impact of
nutrients on immune system is a point of growing research interest. Recent studies have …