Gonadotropin releasing hormone (GnRH) is a highly conserved neuroendocrine
decapeptide that is essential for the onset of puberty and the maintenance of the …

In humans, as in the other mammals, the neuroendocrine control of reproduction is ensured
by the brain-pituitary gonadotropic axis. Multiple internal and environmental cues are …

Gonadotropin hormone-releasing hormone (GnRH) is the key regulator of the reproductive
axis. Its pulsatile secretion determines the pattern of secretion of the gonadotropins follicle …

The reproductive system is controlled by gonadotropin releasing hormone (GnRH) secretion
from the brain, which is finely modulated by a number of factors including gonadal sex …

Acquisition of a mature pattern of gonadotropin-releasing hormone (GnRH) secretion from
the CNS is a hallmark of the pubertal process. Little is known about GnRH release during …

Gonadotrophin‐releasing hormone (GnRH) is the primary hypothalamic factor responsible
for the control of gonadotrophin secretion in vertebrates. However, within the last decade …

The hypothalamus integrates endogenous and exogenous inputs to control the pituitary–
gonadal axis. The ultimate hypothalamic influence on reproductive activity is mediated …

The status of the neuroendocrine reproductive axis differs dramatically during various stages
of development, and also differs in several critical ways between the sexes, including its …

Puberty is a transition period of reproductive development from juvenile stages to adulthood
and depends upon the activity of gonadotropin-releasing hormone (GnRH) neurons. GnRH …

A century of research has shown that in rodents, as in higher mammals, puberty is initiated
by the activation of the hypothalamic–pituitary–gonadal axis, and specifically, by the release …