Role of oxidants in male infertility: rationale, significance, and treatment

A Agarwal, RA Saleh - Urologic Clinics, 2002 - urologic.theclinics.com
Recently, the generation of oxidants, also described as reactive oxygen species (ROS), in
the male reproductive tract has become a real concern because of their potential toxic …

Oxidative stress and sperm function: A systematic review on evaluation and management

S Dutta, A Majzoub, A Agarwal - Arab journal of urology, 2019 - Taylor & Francis
Objective: To review and present the most distinct concepts on the association of reactive
oxygen species (ROS) with male reproduction. Methods: The Preferred Reporting Items for …

[HTML][HTML] Male infertility and oxidative stress: a focus on the underlying mechanisms

RJ Aitken, JR Drevet, A Moazamian, P Gharagozloo - Antioxidants, 2022 - mdpi.com
Reactive oxygen species (ROS) play a critical role in defining the functional competence of
human spermatozoa. When generated in moderate amounts, ROS promote sperm …

Water-and fat-soluble antioxidants in human seminal plasma and serum of fertile males

G Lazzarino, I Listorti, G Bilotta, T Capozzolo… - Antioxidants, 2019 - mdpi.com
Reactive oxygen species (ROS) are physiologically involved in functions like sperm
maturation, capacitation and acrosome reaction, but their excess is involved in male …

[HTML][HTML] Diet and men's fertility: does diet affect sperm quality?

FL Nassan, JE Chavarro, C Tanrikut - Fertility and sterility, 2018 - Elsevier
Male contribution to a couple's fecundity is important, and identifying the dietary factors that
can influence male fertility potential is of high importance. Despite this importance, there are …

Oxidative stress and male infertility

S Bisht, M Faiq, M Tolahunase, R Dada - Nature Reviews Urology, 2017 - nature.com
DNA damage, largely owing to oxidative stress, is a leading cause of defective sperm
function. High levels of oxidative stress result in damage to sperm DNA, RNA transcripts …

Oxidative stress and the etiology of male infertility

RJ Aitken - Journal of assisted reproduction and genetics, 2016 - Springer
One of the few insights we have gained into the etiology of male infertility over the past 20
years has been the realization that these cells, and the precious cargos they carry, are …

Reactive oxygen species in seminal plasma as a cause of male infertility

N Kumar, AK Singh - Journal of gynecology obstetrics and human …, 2018 - Elsevier
Male factor is responsible for 40–50% of infertility cases, contributing equally as a female
factor. Oxidative stress has now emerged as one of the major causes of unexplained male …

Sperm DNA damage caused by oxidative stress: modifiable clinical, lifestyle and nutritional factors in male infertility

C Wright, S Milne, H Leeson - Reproductive biomedicine online, 2014 - Elsevier
DNA fragmentation is an important factor in the aetiology of male infertility. However, it is still
underevaluated and its inclusion in routine semen analysis is debated. DNA fragmentation …

[HTML][HTML] Pharmacology of free radicals and the impact of reactive oxygen species on the testis

JS Aprioku - Journal of reproduction & infertility, 2013 - ncbi.nlm.nih.gov
The role of free radicals in normal cellular functions and different pathological conditions has
been a focus of pharmacological studies in the recent past. Reactive oxygen species (ROS) …