Background The genetic network of the TOL plasmid pWW0 of the soil bacterium
Pseudomonas putida mt-2 for catabolism of m-xylene is an archetypal model for …

The structure of the extant transcriptional control network of the TOL plasmid pWW0 born by
Pseudomonas putida mt‐2 for biodegradation of m‐xylene is far more complex than one …

The TOL system encoded by plasmid pWW0 of P seudomonas putida mt‐2 is able to sense
a large number of both exogenous and endogenous signals as inputs for the genetic and …

A subgenomic array of structural and regulatory genes of the TOL plasmid pWW0 of
Pseudomonas putida mt‐2 has been constructed to sort out the interplay between m‐xylene …

The first mechanistic description of gene expression control was proposed by Jacob and
Monod (1961) for the lac operon of E. coli. The first version of the model contemplated …

P seudomonas putida mt‐2 metabolizes m‐xylene and other aromatic compounds through
the enzymes encoded by the xyl operons of the TOL plasmid p WW0 along with other …

The expression dynamics of the catabolic promoters of the TOL plasmid pWW0 has been
examined in single cells of Pseudomonas putida mt‐2 exposed to m‐xylene. To this end, we …

Prokaryotic transcription factors (TFs) that bind small xenobiotic molecules (eg, TFs that
drive genes that respond to environmental pollutants) often display a promiscuous effector …

Pseudomonas putida MT53 contains a TOL plasmid, pWW53, that encodes toluene-xylene
catabolism. pWW53 is nonconjugative, is about 105 to 110 kilobase pairs (kbp) in size, and …

The TOL plasmid promoters are activated by toluene leading to gene expression
responsible for the degradation of the environmental signal. Benzoate is formed as an …