Genome-Wide Identification of Potential Drug Target in Enterobacteriaceae Family: A Homology-Based Method

M Hadizadeh, SN Tabatabaiepour… - Microbial Drug …, 2018 - liebertpub.com
The Enterobacteriaceae is a large family of Gram-negative, facultative anaerobic, non-spore
forming rod-shaped bacteria that includes harmless and pathogenic organisms. The …

In Silico Identification of Probable Drug and Vaccine Candidates Against Antibiotic-Resistant Acinetobacter baumannii

E Zadeh Hosseingholi, G Zarrini… - Microbial Drug …, 2020 - liebertpub.com
Acinetobacter baumannii is known as a Gram-negative bacterium that has become one of
the most important health problems due to antibiotic resistance. Today, numerous efforts are …

In Silico Identification and Characterization of Drug Targets in Streptococcus pneumoniae ATCC 700669 (Serotype 23F) by Subtractive Genomics

T Duguma, H Dinka - BioMed Research International, 2024 - Wiley Online Library
Streptococcus pneumoniae (S. pneumoniae) is an important pathogen worldwide that
causes pneumococcal infections which are related to high rates of morbidity and mortality …

Pangenome profiling of novel drug target against vancomycin-resistant Enterococcus faecium

K Khan, K Jalal, R Uddin - Journal of Biomolecular Structure and …, 2023 - Taylor & Francis
Enterococcus faecium is a frequent causative agent of nosocomial infection mainly acquired
from outgoing hospital patients (Hospital Acquired Infection—HAIs). They are largely …

Computational screening of potential drug targets for pathogens causing bacterial pneumonia

S Nayak, D Pradhan, H Singh, MS Reddy - Microbial pathogenesis, 2019 - Elsevier
Streptococcus pneumoniae is widely recognized as the main cause of bacterial pneumonia
among all age groups. Other important gram-positive, gram-negative and atypical bacteria …

Elucidating vital drug targets of Salmonella enterica utilizing the bioinformatic approach

A Verma, N Goel, V Laxmi, B Rathi… - Journal of …, 2016 - search.proquest.com
Salmonella enterica, a rod shaped gram-negative bacterium is a major cause of
salmonellosis worldwide inducing enteritis and typhoid fever. It is necessary to seek out its …

Rational identification of new antibacterial drug targets that are essential for viability using a genomics-based approach

AF Chalker, RD Lunsford - Pharmacology & therapeutics, 2002 - Elsevier
In the last two decades, the search for completely novel antibacterial agents has acquired a
new sense of urgency due to the remarkable rise of antibiotic resistance among key …

Identification and functional annotation of hypothetical proteins of uropathogenic Escherichia coli strain CFT073 towards designing antimicrobial drug targets

H Kaur, V Singh, M Kalia, B Mohan… - Journal of Biomolecular …, 2022 - Taylor & Francis
Urinary tract infections are a serious health concern worldwide, especially in developing
countries. Escherichia coli strain CFT073 is a highly virulent pathogenic bacterial strain …

[PDF][PDF] In silico identification of novel drug targets in acinetobacter baumannii by subtractive genomic approach

M Goyal, C Citu, N Singh - Asian J. Pharm. Clin. Res, 2018 - researchgate.net
Objective: Multiple drug resistance (MDR) in bacteria, particularly Gram-negative bacilli, has
significantly hindered the treatment of infections caused by these bacteria. This results in the …

[PDF][PDF] In silico drug targets for infective endocarditis

V Priyadarshini, D Pradhan, M Munikumar… - Online Journal of …, 2013 - researchgate.net
ABSTRACT Priyadarshini V, Pradhan D, Munikumar M, Swargam S, Umamaheswari A,
Rajasekhar D., In silico drug targets for infective endocarditis, Online J Bioinform14 (1): 32 …