Malignant cells have the capacity to rapidly grow exponentially and spread in part by
suppressing, evading, and exploiting the host immune system. Immunotherapy is a form of …

Cancer is a worldwide medical problem with significant repercussions on individual patients
and societies as a whole. In order to alter the outcomes of this deadly disease the treatment …

These are exciting times for cancer immunotherapy. After many years of disappointing
results, the tide has finally changed and immunotherapy has become a clinically validated …

Blocking antibodies to the immune checkpoint receptors or their ligands have revolutionized
the treatment of diverse malignancies. Many tumors are recognized by adaptive immunity …

Immunology-based therapy is rapidly developing into an effective treatment option for a
surprising range of cancers. We have learned over the last decade that powerful …

Traditional cancer therapies include surgery, radiation, and chemotherapy, all of which are
typically non-specific approaches. Cancer immunotherapy is a type of cancer treatment that …

Cancer immunotherapy has dramatically changed the approach to cancer treatment. The
aim of targeting the immune system to recognize and destroy cancer cells has afforded …

Recent advances in cancer treatment have emerged from new immunotherapies targeting T-
cell inhibitory receptors, including cytotoxic T-lymphocyte associated antigen (CTLA)-4 and …

Traditional treatment modalities for advanced cancer (radiotherapy, chemotherapy, or
targeted agents) act directly on tumors to inhibit or destroy them. Along with surgery, these …

For many years, immunotherapeutic approaches for cancer held more promise than actual
clinical benefit for the majority of patients. However, several recent key advances in tumor …