Systemic inflammatory markers in patients with polyneuropathies

P García-Fernández, K Höfflin, A Rausch… - Frontiers in …, 2023 - frontiersin.org
Introduction In patients with peripheral neuropathies (PNP), neuropathic pain is present in
50% of the cases, independent of the etiology. The pathophysiology of pain is poorly …

Increased pro-inflammatory cytokine gene expression in peripheral blood mononuclear cells of patients with polyneuropathies

M Langjahr, AL Schubert, C Sommer, N Üçeyler - Journal of Neurology, 2018 - Springer
Background Distinct cytokine expression patterns have been reported in biomaterial of
patients with polyneuropathies (PNP). We investigated gene expression profiles of pro-and …

Cytokine expression in serum and cerebrospinal fluid in non-inflammatory polyneuropathies

J Ludwig, A Binder, J Steinmann, G Wasner… - Journal of Neurology …, 2008 - jnnp.bmj.com
Background: Pain is a common symptom in polyneuropathies (PNPs), although it is still not
known why some PNPs are painful and others are painless. Increased pro-inflammatory …

[HTML][HTML] Pro-inflammatory cytokines and leukocyte integrins associated with chronic neuropathic pain in traumatic and inflammatory neuropathies: Initial observations …

C Dong, EE Ubogu - Frontiers in Immunology, 2022 - frontiersin.org
Leukocyte infiltration and persistence within peripheral nerves have been implicated in
chronic nociception pathogenesis in murine peripheral neuropathy models. Endoneurial …

Differential expression of cytokines in painful and painless neuropathies

N Uceyler, JP Rogausch, KV Toyka, C Sommer - Neurology, 2007 - AAN Enterprises
Background: Pain is a common symptom in peripheral neuropathies. The factors
determining why some peripheral neuropathies are painful and others are not are …

Cytokine-related and histological biomarkers for neuropathic pain assessment

N Üçeyler, C Sommer - Pain management, 2012 - Taylor & Francis
Neuropathic pain (NP) is a disabling condition that may occur following a disease or a lesion
of the somatosensory nervous system. With an estimated prevalence of up to 8.2% in the …

Differential association between biomarkers of subclinical inflammation and painful polyneuropathy: results from the KORA F4 study

C Herder, BWC Bongaerts, W Rathmann… - Diabetes …, 2015 - Am Diabetes Assoc
OBJECTIVE Inflammatory processes have been implicated in the pathogenesis of painful
neuropathy in rodents, but the relationship between inflammatory biomarkers and painful …

[HTML][HTML] Neuroimmune interactions in peripheral neuropathy

J Yang, A Yaron, K Liu - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Peripheral neuropathy is a collection of neurodegenerative conditions in the peripheral
nervous system (PNS), particularly involving damage or loss of sensory, motor, or autonomic …

Myelination, axonal loss and Schwann cell characteristics in axonal polyneuropathy compared to controls

E Placheta-Györi, LM Brandstetter, J Zemann-Schälss… - Plos one, 2021 - journals.plos.org
Introduction Polyneuropathy is a debilitating condition characterized by distal sensory and
motor deficits. Schwann cell dysfunction and axonal loss are integral factors in …

Nerve biopsy in chronic inflammatory neuropathies: in situ biomarkers

C Sommer, K Toyka - Journal of the Peripheral Nervous …, 2011 - Wiley Online Library
We collected the evidence for potential biomarkers in nerve biopsies that might be of use in
diagnosis, assessment, or treatment response in chronic inflammatory demyelinating …