Cathepsin G (CathG) is a serine protease that controls the functional state of immune cells
and is traditionally considered to be one of the effectors of inflammation (1). The substrate …

Cathepsin G (CatG) is involved in controlling numerous processes of the innate and
adaptive immune system. These features include the proteolytic activity of CatG and play a …

Cathepsin G belongs to the neutrophil serine proteases family, known for its function in
killing pathogens. Studies over the past several years indicate that cathepsin G has …

Contributions from multiple cathepsins within endosomal antigen processing compartments
are necessary to process antigenic proteins into antigenic peptides. Cysteine and aspartyl …

Cathepsin E is an intracellular aspartic proteinase of the pepsin superfamily, which is
predominantly expressed in certain cell types, including the immune system cells and …

Cathepsin X, a cysteine protease, has been shown to regulate an immune response by
activating β-2 integrin receptors. In this study we demonstrate its role in regulating the …

Objective Cathepsin K is a lysosomal cysteine protease that has pleiotropic roles in bone
resorption, arthritis, atherosclerosis, blood pressure regulation, obesity and cancer …

Human neutrophils express at least four active serine proteases, cathepsin G, N-elastase,
proteinase 3 and neutrophil serine protease 4 (NSP4). They have all been extensively …

The cathepsins are a group of homologous proteases that can be found in a wide variety of
cell types [1]. In the last decade, much attention has been given to one of the members of the …

Cathepsins are required for the processing of antigens in order to make them suitable for
loading on major histocompatibility complex (MHC) class II molecules, for subsequent …