Variational graph auto-encoders for miRNA-disease association prediction

Y Ding, LP Tian, X Lei, B Liao, FX Wu - Methods, 2021 - Elsevier
Cumulative experimental studies have demonstrated the critical roles of microRNAs
(miRNAs) in the diverse fundamental and important biological processes, and in the …

[HTML][HTML] GCAEMDA: Predicting miRNA-disease associations via graph convolutional autoencoder

L Li, YT Wang, CM Ji, CH Zheng, JC Ni… - PLOS Computational …, 2021 - journals.plos.org
microRNAs (miRNAs) are small non-coding RNAs related to a number of complicated
biological processes. A growing body of studies have suggested that miRNAs are closely …

Predicting miRNA-disease associations based on multi-view variational graph auto-encoder with matrix factorization

Y Ding, X Lei, B Liao, FX Wu - IEEE journal of biomedical and …, 2021 - ieeexplore.ieee.org
MicroRNAs (miRNAs) have been proved to play critical roles in diverse biological
processes, including the human disease development process. Exploring the potential …

[HTML][HTML] Predicting miRNA-disease associations based on graph attention network with multi-source information

G Li, T Fang, Y Zhang, C Liang, Q Xiao, J Luo - BMC bioinformatics, 2022 - Springer
Background There is a growing body of evidence from biological experiments suggesting
that microRNAs (miRNAs) play a significant regulatory role in both diverse cellular activities …

[HTML][HTML] Hierarchical graph attention network for miRNA-disease association prediction

Z Li, T Zhong, D Huang, ZH You, R Nie - Molecular Therapy, 2022 - cell.com
Many biological studies show that the mutation and abnormal expression of microRNAs
(miRNAs) could cause a variety of diseases. As an important biomarker for disease …

Predicting miRNA-disease associations from miRNA-gene-disease heterogeneous network with multi-relational graph convolutional network model

W Peng, Z Che, W Dai, S Wei… - IEEE/ACM Transactions …, 2022 - ieeexplore.ieee.org
MiRNAs are reported to be linked to the pathogenesis of human complex diseases. Disease-
related miRNAs may serve as novel bio-marks and drug targets. This work focuses on …

Predicting miRNA-disease associations via node-level attention graph auto-encoder

H Zhang, J Fang, Y Sun, G Xie, Z Lin… - IEEE/ACM Transactions …, 2022 - ieeexplore.ieee.org
Previous studies have confirmed microRNA (miRNA), small single-stranded non-coding
RNA, participates in various biological processes and plays vital roles in many complex …

PDMDA: predicting deep-level miRNA–disease associations with graph neural networks and sequence features

C Yan, G Duan, N Li, L Zhang, FX Wu, J Wang - Bioinformatics, 2022 - academic.oup.com
Motivation Many studies have shown that microRNAs (miRNAs) play a key role in human
diseases. Meanwhile, traditional experimental methods for miRNA–disease association …

Semi-supervised prediction of human miRNA-disease association based on graph regularization framework in heterogeneous networks

J Luo, P Ding, C Liang, X Chen - Neurocomputing, 2018 - Elsevier
MicroRNAs (miRNAs) play important roles in the various pathogenesis of diseases.
However, experimental prediction of associations between microRNAs and diseases …

[HTML][HTML] Prediction of potential mirna–disease associations through a novel unsupervised deep learning framework with variational autoencoder

L Zhang, X Chen, J Yin - Cells, 2019 - mdpi.com
The important role of microRNAs (miRNAs) in the formation, development, diagnosis, and
treatment of diseases has attracted much attention among researchers recently. In this study …