Fibroblast growth factor–23 and cardiac structure and function
Background Fibroblast growth factor–23 (FGF‐23) is a phosphaturic factor previously
associated with left ventricular hypertrophy and systolic dysfunction among individuals with …
associated with left ventricular hypertrophy and systolic dysfunction among individuals with …
FGF23 induces left ventricular hypertrophy
Chronic kidney disease (CKD) is a public health epidemic that increases risk of death due to
cardiovascular disease. Left ventricular hypertrophy (LVH) is an important mechanism of …
cardiovascular disease. Left ventricular hypertrophy (LVH) is an important mechanism of …
Soluble α-klotho and heparin modulate the pathologic cardiac actions of fibroblast growth factor 23 in chronic kidney disease
Fibroblast growth factor (FGF) 23 is a phosphate-regulating hormone that is elevated in
patients with chronic kidney disease and associated with cardiovascular mortality …
patients with chronic kidney disease and associated with cardiovascular mortality …
Fibroblast growth factor 23 and long-term cardiac function: the multi-ethnic study of atherosclerosis
RB Patel, H Ning, IH De Boer… - Circulation …, 2020 - Am Heart Assoc
Background: Although FGF23 (fibroblast growth factor 23) is associated with heart failure
and atrial fibrillation, the mechanisms driving these associations are unclear. Sensitive …
and atrial fibrillation, the mechanisms driving these associations are unclear. Sensitive …
Paracrine effects of FGF23 on the heart
M Leifheit-Nestler, D Haffner - Frontiers in endocrinology, 2018 - frontiersin.org
Fibroblast growth factor (FGF) 23 is a phosphaturic hormone primarily secreted by
osteocytes to maintain phosphate and mineral homeostasis. In patients with and without …
osteocytes to maintain phosphate and mineral homeostasis. In patients with and without …
Fibroblast growth factor-23 and cardiovascular disease in the general population: the Multi-Ethnic Study of Atherosclerosis
B Kestenbaum, MC Sachs, AN Hoofnagle… - Circulation: Heart …, 2014 - Am Heart Assoc
Background—Fibroblast growth factor-23 (FGF-23) is a phosphate regulatory hormone that
directly stimulates left ventricular hypertrophy in experimental models. The role of FGF-23 in …
directly stimulates left ventricular hypertrophy in experimental models. The role of FGF-23 in …
Association between FGF23, α-Klotho, and cardiac abnormalities among patients with various chronic kidney disease stages
S Tanaka, S Fujita, S Kizawa, H Morita, N Ishizaka - PloS one, 2016 - journals.plos.org
Background Several experimental studies have demonstrated that fibroblast growth factor
23 (FGF23) may induce myocardial hypertrophy via pathways independent of α-Klotho, its …
23 (FGF23) may induce myocardial hypertrophy via pathways independent of α-Klotho, its …
Direct and indirect effects of fibroblast growth factor 23 on the heart
T Nakano, H Kishimoto, M Tokumoto - Frontiers in endocrinology, 2023 - frontiersin.org
Fibroblast growth factor (FGF) 23 is a bone-derived phosphotropic hormone that regulates
phosphate and mineral homeostasis. Recent studies have provided evidence that a high …
phosphate and mineral homeostasis. Recent studies have provided evidence that a high …
Cardiac fibroblast growth factor 23 excess does not induce left ventricular hypertrophy in healthy mice
M Leifheit-Nestler, MA Wagner, B Richter… - Frontiers in cell and …, 2021 - frontiersin.org
Fibroblast growth factor (FGF) 23 is elevated in chronic kidney disease (CKD) to maintain
phosphate homeostasis. FGF23 is associated with left ventricular hypertrophy (LVH) in CKD …
phosphate homeostasis. FGF23 is associated with left ventricular hypertrophy (LVH) in CKD …
Induction of cardiac FGF23/FGFR4 expression is associated with left ventricular hypertrophy in patients with chronic kidney disease
M Leifheit-Nestler, R große Siemer… - Nephrology Dialysis …, 2016 - academic.oup.com
Background In chronic kidney disease (CKD), serum concentrations of fibroblast growth
factor 23 (FGF23) increase progressively as glomerular filtration rate declines, while renal …
factor 23 (FGF23) increase progressively as glomerular filtration rate declines, while renal …