Polymeric nanoparticles (NPs) have great potential application in achieving targeted
delivery of anticancer drugs. Paclitaxel (PTX) loaded NPs were developed using …

To develop potent paclitaxel (PTX) formulations for cancer chemotherapy, we formulated
PTX into polymeric nanoparticles composed of polyethylene glycol (PEG) and polylactic acid …

Abstract Previously, PEGylated paclitaxel (PEG-PTX) was found not favorable as a polymer
prodrug because of its poor antitumor efficiency. But surprisingly, it was found in our study …

Paclitaxel is a diterpenoid isolated from Taxus brevifolia. It is effective for various cancers,
especially ovarian and breast cancer. Due to its aqueous insolubility, it is administered …

Block copolymers composed of poly (3-hydroxyoctanoate)(PHO) and methoxy poly
(ethylene glycol)(PEG) were synthesized to prepare paclitaxel-incorporated nanoparticle for …

Paclitaxel (PTX) is an effective anticancer chemical with a broad spectrum that was primarily
obtained from a curative shrub, specifically the bark of Taxus brevifolia tree. It belongs to a …

In this paper, an overview of recent advances of paclitaxel formulations based on
nanosystems is provided. Paclitaxel is very effective in the treatment of various cancers …

Nanomedicines have become an attractive platform for the development of novel drug
delivery systems in cancer chemotherapy. Polymeric nanoparticles (NPs) represent one of …

Paclitaxel (PTX) is a natural broad-spectrum anticancer drug with poor aqueous solubility.
PTX nanocrystals were formulated to improve the water solubility, and PTX …

Objective The aim of the study was to develop stable Paclitaxel nanocrystals (PTX/NCs) for
enhanced oral delivery of Paclitaxel (PTX) by circumventing its difficult solubilization …