Neuronal changes in psoriasis exacerbation

H El‐Nour, A Santos, M Nordin… - Journal of the …, 2009 - Wiley Online Library
Background The nervous system contributes to inflammatory skin diseases. Objective The
aim of this investigation was to study the neuronal contribution to psoriasis at the remission …

Double‐labeled immunofluorescence study of cutaneous nerves in psoriasis

WY Jiang, SP Raychaudhuri… - International journal of …, 1998 - Wiley Online Library
Background and objective In recent years, many reports have suggested an active role of
neuropeptides in the pathogenesis of psoriasis. Increased numbers of neuropeptide …

Study of substance P and its receptor neurokinin-1 in psoriasis and their relation to chronic stress and pruritus

C Remröd, S Lonne-Rahm, K Nordlind - Archives of dermatological …, 2007 - Springer
Substance P and its receptor (R) neurokinin (NK)-1 may have a role in the pathogenesis of
psoriasis. Stress has been reported to play a role in the onset and exacerbation of psoriasis …

Immunohistochemical study of epidermal nerve fibres in involved and uninvolved psoriatic skin using confocal laser scanning microscopy

S Pergolizzi, M Vaccaro, L Magaudda… - Archives of …, 1998 - Springer
Psoriasis is a typical hyperproliferative epidermal disease whose aetiopathogenesis is still
to be defined. One of the most likely hypotheses is that it has a neurogenic origin correlated …

Effects on peripheral and central nervous system of key inflammatory intercellular signalling peptides and proteins in psoriasis

J Tang, S Zhao, H Shi, X Li, L Ran… - Experimental …, 2024 - Wiley Online Library
Psoriasis is a chronic systemic inflammatory cutaneous disease. Where the immune system
plays an important role in its pathogenesis, with key inflammatory intercellular signalling …

Role of neuroimmune circuits and pruritus in psoriasis

MT Ayasse, J Buddenkotte, M Alam… - Experimental …, 2020 - Wiley Online Library
Psoriasis is a chronic inflammatory skin disease presenting with an array of clinical
phenotypes, often associated with pruritus. Environmental and psychological stressors can …

Quantification of cutaneous sensory nerves and their substance P content in psoriasis

A Naukkarinen, BJ Nickoloff, EM Farber - Journal of investigative …, 1989 - Elsevier
The aim of the present study was to extend our previous hypothesis that the inflammatory
reaction in psoriasis is rogenic, and that substance P mediates the inflammation. For this …

Is psoriasis a neuroimmunologic disease?

EM Farber, SP Raychaudhuri - International journal of …, 1999 - search.ebscohost.com
Examines the role of neurogenic inflammation in the pathogenesis of psoriasis. Correlation
between high levels of keratinocytes and the upregulation of neuropeptides in psoriatic …

[引用][C] Psychoneuroimmunology and dermatology

EM FARBER - International journal of dermatology, 1993 - Wiley Online Library
At the PRI, we have drawn on some of the latest investigative findings from
psychoneuroimmunology to gain insight into the pathodynamics of the relationship between …

Neurotransmitters, neuropeptides and their receptors interact with immune response in healthy and psoriatic skin

AK Sandoval-Talamantes, BA Gómez-González… - Neuropeptides, 2020 - Elsevier
Psoriasis is a chronic inflammatory disease with a multifactorial origin that affects the skin. It
is characterized by keratinocyte hyperproliferation, which results in erythemato-squamous …