Chronic pain is associated with anhedonia and decreased motivation. These behavioral
alterations have been linked to alterations in the limbic brain and could explain the …

Chronic low back pain (CLBP) and obesity are interrelated, but the physiological
mechanisms linking the 2 conditions remain to be determined. Functional brain imaging …

Sufferers of persistent pain have increased risk for many other health problems, including
obesity. The mechanisms have not been well understood, however. In this issue, Geha et al …

Providers frequently report pain as a barrier to weight loss, and initial evidence suggests
individuals with chronic pain and obesity experience reduced treatment success. However …

Introduction A bidirectional relationship exists between obesity and chronic pain. How the
two variables influence one another is unclear, especially in the context of prescription …

Objectives Chronic pain and obesity are major public health concerns. Animal and human
models have demonstrated that eating high-sugar nutrient-dense foods confers analgesic …

Chronic pain may sap the motivation for positive events and stimuli. This may lead to a
negative behavioural cycle reducing the establishment of appetitive habitual engagement …

The obesity epidemic in the US and abroad has increased interest in neurobiological
mechanisms that contribute to eating in the absence of energy demand or hunger …

Background Chronic pain and higher body weight frequently co-occur. This common
comorbidity is thought to be mediated by the use of comfort eating as a strategy for …

A common complaint among pain patients is that they lose their appetite. These accounts
are anecdotal, however, and the neural mechanism underlying pain-induced loss of appetite …