Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disease in women
of reproductive age. Ovarian dysfunction including abnormal steroid hormone synthesis and …

Polycystic ovary syndrome (PCOS) is the most common complex endocrine and metabolic
disease in women of reproductive age. It is characterized by anovulatory infertility, hormone …

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women at
reproductive age. However, the underlying pathogenic mechanisms have not been …

Intraovarian hyperandrogenism is one of the determining factors of follicular arrest in women
with polycystic ovary syndrome (PCOS). Using androgenized rat models, we investigated …

Background To explore the development mechanism of PCOS and Transcriptomics was
applied to seek the key gene. Methods Transcriptomics marked by UID (unique identifier) …

Ovarian granulosa cells display strong androgen receptor (AR) expression, suggesting a
functional role for direct AR-mediated actions within developing mammalian follicles. By …

Background Polycystic ovary syndrome (PCOS) is one of the most incident reproductive
diseases, and remains the main cause of female infertility. Granulosa cells play a critical role …

Background Androgen excess could profoundly lead to follicular dysplasia or atresia, and
finally result in polycystic ovary syndrome (PCOS); however, the exact mechanism remains …

Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by
hyperandrogenemia of ovarian thecal cell origin, resulting in anovulation/oligo-ovulation …

Background Disordered folliculogenesis is a core characteristic of polycystic ovary
syndrome (PCOS) and androgen receptors (ARs) are closely associated with …