Disease severity and symptoms among patients receiving monotherapy for COPD

MT Dransfield, W Bailey, G Crater, A Emmett… - Primary Care …, 2011 - nature.com
Aim: To examine the burden of respiratory symptoms, quality of life and co-morbid illness in
COPD patients receiving maintenance treatment in a real world setting. Methods: In a single …

Relationship between FEV1 change and patient-reported outcomes in randomised trials of inhaled bronchodilators for stable COPD: a systematic review

M Westwood, J Bourbeau, PW Jones, A Cerulli… - Respiratory …, 2011 - Springer
Background Interactions between spirometry and patient-reported outcomes in COPD are
not well understood. This systematic review and study-level analysis investigated the …

Effect of inhaled bronchodilators on inspiratory capacity and dyspnoea at rest in COPD

F Di Marco, J Milic-Emili, B Boveri… - European …, 2003 - Eur Respiratory Soc
It has been shown that patients with chronic obstructive pulmonary disease (COPD) develop
dynamic hyperinflation (DH), which contributes to dyspnoea and exercise intolerance …

[HTML][HTML] Stepwise withdrawal of inhaled corticosteroids in COPD patients receiving dual bronchodilation: WISDOM study design and rationale

H Magnussen, H Watz, A Kirsten, M Decramer… - Respiratory …, 2014 - Elsevier
Long-acting bronchodilators in combination with inhaled corticosteroids (ICS) are
recommended to decrease the risk of recurrent exacerbations in patients with Global …

Bronchodilators in COPD: impact of β-agonists and anticholinergics on severe exacerbations and mortality

SR Salpeter - … Journal of Chronic Obstructive Pulmonary Disease, 2007 - Taylor & Francis
This review summarizes the long-term clinical outcomes associated with β-agonist and
anticholinergic bronchodilator use in patients with chronic obstructive pulmonary disease …

Diagnostic value of post-bronchodilator pulmonary function testing to distinguish between stable, moderate to severe COPD and asthma

DC Richter, JR Joubert, H Nell… - … Journal of Chronic …, 2008 - Taylor & Francis
Objective The GOLD guidelines suggest that the presence of a post-bronchodilator forced
expiratory volume in one second (FEV1)< 80% of the predicted value in combination with a …

Factor analysis of changes in dyspnea and lung function parameters after bronchodilation in chronic obstructive pulmonary disease

C Taube, B Lehnigk, K Paasch… - American journal of …, 2000 - atsjournals.org
Expiratory airway collapse is a characteristic feature in patients with chronic obstructive
pulmonary disease (COPD). We hypothesized that this collapse might mask the effects of …

COPD: maximization of bronchodilation

S Nardini, G Camiciottoli, S Locicero, R Maselli… - Multidisciplinary …, 2014 - Springer
The most recent guidelines define COPD in a multidimensional way, nevertheless the
diagnosis is still linked to the limitation of airflow, usually measured by the reduction in the …

Concurrent use of long-acting bronchodilators in COPD and the risk of adverse cardiovascular events

S Suissa, S Dell'Aniello, P Ernst - European Respiratory …, 2017 - Eur Respiratory Soc
The cardiovascular risk of concurrently using long-acting β2-agonists (LABAs) and
anticholinergics (LAMAs) in COPD is uncertain. We assessed the comparative …

Characteristics of patients with COPD newly prescribed a long-acting bronchodilator: a retrospective cohort study

KE Wurst, S St Laurent, H Mullerova… - International journal of …, 2014 - Taylor & Francis
Introduction This study aimed to characterize patients with chronic obstructive pulmonary
disease (COPD) newly prescribed a long-acting bronchodilator (LABD), and to assess …