Association of pre-admission statin use with reduced in-hospital mortality in COVID-19

SR Chacko, R DeJoy III, KB Lo, J Albano… - The American Journal of …, 2021 - Elsevier
Abstract Background Coronavirus disease-19 (COVID-19) infection is associated with an
uncontrolled systemic inflammatory response. Statins, given their anti-inflammatory …

[HTML][HTML] The effect of statins on clinical outcome among hospitalized patients with COVID-19: a multi-centric cohort study

S Umakanthan, S Senthil, S John… - Frontiers in …, 2022 - frontiersin.org
The coronavirus disease-2019 (COVID-19) is caused by SARS-CoV-2, leading to acute
respiratory distress syndrome (ARDS), thrombotic complications, and myocardial injury …

[HTML][HTML] In-hospital use of statins is associated with a reduced risk of mortality in coronavirus-2019 (COVID-19): systematic review and meta-analysis

H Permana, I Huang, A Purwiga… - Pharmacological …, 2021 - Springer
Background and aims The idea of treating COVID-19 with statins is biologically plausible,
although it is still controversial. The systematic review and meta-analysis aimed to address …

[HTML][HTML] Statin use is associated with a decreased risk of mortality among patients with COVID-19

CC Wu, AJ Lee, CH Su, CY Huang, MM Islam… - Journal of Clinical …, 2021 - mdpi.com
Background: Recent epidemiological studies remain controversial regarding the association
between statin use and reducing the risk of mortality among individuals with COVID-19 …

[HTML][HTML] Statins use and COVID-19 outcomes in hospitalized patients

SK Ayeh, EJ Abbey, BAA Khalifa, RD Nudotor… - PLoS …, 2021 - journals.plos.org
Background There is an urgent need for novel therapeutic strategies for reversing COVID-19-
related lung inflammation. Recent evidence has demonstrated that the cholesterol-lowering …

[HTML][HTML] Association of statin use with the in-hospital outcomes of 2019-coronavirus disease patients: a retrospective study

Y Fan, T Guo, F Yan, M Gong, XA Zhang, C Li… - Frontiers in …, 2020 - frontiersin.org
Background: Statins have multiple protective effects on inflammation, immunity and
coagulation, and may help alleviate pneumonia. However, there was no report focusing on …

[HTML][HTML] Efficacy of statin therapy in patients with hospital admission for COVID-19

D Choi, Q Chen, SN Goonewardena… - … Drugs and Therapy, 2021 - Springer
Purpose COVID-19 is characterized by dysfunctional immune responses and metabolic
derangements, which in some, lead to multi-organ failure and death. Statins are …

[HTML][HTML] Statin use and in-hospital mortality in patients with COVID-19 and coronary heart disease

L Shen, L Qiu, L Wang, H Huang, D Liu, Y Xiao… - Scientific Reports, 2021 - nature.com
The worsening progress of coronavirus disease 2019 (COVID-19) is attributed to the
proinflammatory state, leading to increased mortality. Statin works with its anti-inflammatory …

Beneficial effect of statins in COVID-19–related outcomes—brief report: a national population-based cohort study

HY Lee, J Ahn, J Park, C Kyung Kang… - … , and vascular biology, 2021 - Am Heart Assoc
Objective: Although statins are widely prescribed lipid-lowering drugs, there are concerns
about the safety of their use in the context of coronavirus disease 2019 (COVID-19), since …

[HTML][HTML] Association between antecedent statin use and decreased mortality in hospitalized patients with COVID-19

A Gupta, MV Madhavan, TJ Poterucha… - Nature …, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) can result in a hyperinflammatory state,
leading to acute respiratory distress syndrome (ARDS), myocardial injury, and thrombotic …