As an increasing public health concern worldwide, acute kidney injury (AKI) is characterized
by rapid deterioration of kidney function. Although continuous renal replacement therapy …

The aim of the present study was to investigate the protective effect and underlying
mechanism of tetramethylpyrazine (TMP) on renal ischemia reperfusion injury (RIRI) in rats …

Objectives. Acute kidney injury (AKI) is a loose set of kidney diseases accompanied by a
variety of syndromes, which is a serious threat to human life and health. Some alkaloids are …

Tetramethylpyrazine (TMP), a compound purified from Rhizoma Ligustici, is a widely used
active ingredient in Chinese herbal medicine to treat cardiovascular diseases on account of …

Acute kidney injury (AKI) is a clinical syndrome characterized by a rapid loss of renal
function, which may further develop into chronic kidney damage (CKD) or even end-stage …

Gentamycin is an aminoglycoside antibiotic that is widely employed for controlling Gram
negative bacterial infections including that caused by the antibiotic-resistant Pseudomonas …

Acute kidney injury (AKI) is a common and independent risk factor for death and chronic
kidney disease (CKD). Despite promising preclinical data, there is no evidence that …

Cryptotanshinone (CTS) is a natural compound from the Chinese herb Salvia miltiorrhiza.
Previous studies demonstrated that CTS possesses anti‐apoptotic and anti‐inflammatory …

Background. Gentamicin, a widely used antibiotic for the treatment of bacterial infection, can
cause nephrotoxicity. Tetramethylpyrazine (TMP) is a compound purified from the rhizome of …

In the present study, the protective effect and the potential underlying mechanism of
rutaecarpine (Ru) on renal ischemia reperfusion injury (IRI) in rats were investigated. A renal …