The role of melanin in fungal pathogenesis for animal hosts
DFQ Smith, A Casadevall - Fungal physiology and immunopathogenesis, 2019 - Springer
Melanins are a class of pigments that are ubiquitous throughout biology. They play
incredibly diverse and important roles ranging from radiation protection to immune defense …
incredibly diverse and important roles ranging from radiation protection to immune defense …
The role of melanins in melanotic fungi for pathogenesis and environmental survival
HC Eisenman, EM Greer, CW McGrail - Applied microbiology and …, 2020 - Springer
Melanins provide fungi protection from environmental stressors, support their ecological
roles, and can confer virulence in pathogens. While the function, structure, and synthesis of …
roles, and can confer virulence in pathogens. While the function, structure, and synthesis of …
Fungal melanin and the mammalian immune system
S Liu, S Youngchim, D Zamith-Miranda, JD Nosanchuk - Journal of Fungi, 2021 - mdpi.com
Melanins are ubiquitous complex polymers that are commonly known in humans to cause
pigmentation of our skin. Melanins are also present in bacteria, fungi, and helminths. In this …
pigmentation of our skin. Melanins are also present in bacteria, fungi, and helminths. In this …
Functions of fungal melanin beyond virulence
RJB Cordero, A Casadevall - Fungal Biology Reviews, 2017 - Elsevier
Melanins are ancient biological pigments found in all kingdoms of life. In fungi, their role in
microbial pathogenesis is well established; however, these complex biomolecules also …
microbial pathogenesis is well established; however, these complex biomolecules also …
Pathogenic properties of fungal melanins
MJ Butler, AW Day, JM Henson, NP Money - Mycologia, 2001 - Taylor & Francis
Melanins are complex black polymers of resonance stabilized cyclic subunits (including
indoles, phenols, hydroxynaphthalenes) and are notoriously intractable to chemical …
indoles, phenols, hydroxynaphthalenes) and are notoriously intractable to chemical …
Biosynthesis of fungal melanins and their importance for human pathogenic fungi
K Langfelder, M Streibel, B Jahn, G Haase… - Fungal genetics and …, 2003 - Elsevier
For more than 40 years fungi have been known to produce pigments known as melanins.
Predominantly these have been dihydroxyphenylalanine (DOPA)-melanin and …
Predominantly these have been dihydroxyphenylalanine (DOPA)-melanin and …
The contribution of melanin to microbial pathogenesis
JD Nosanchuk, A Casadevall - Cellular microbiology, 2003 - Wiley Online Library
Melanins are enigmatic pigments that are produced by a wide variety of microorganisms
including several species of pathogenic bacteria, fungi and helminthes. The study of …
including several species of pathogenic bacteria, fungi and helminthes. The study of …
Degradation of melanin or inhibition of its synthesis: are these a significant approach as a biological control of phytopathogenic fungi?
MJ Butler, RB Gardiner, AW Day - Biological Control, 2005 - Elsevier
Many fungal plant pathogens produce melanins that play direct or indirect roles in the
infection process. Destruction of the melanin or inhibition of its synthesis by biological …
infection process. Destruction of the melanin or inhibition of its synthesis by biological …
Impact of melanin on microbial virulence and clinical resistance to antimicrobial compounds
JD Nosanchuk, A Casadevall - Antimicrobial agents and …, 2006 - Am Soc Microbiol
Melanins are negatively charged, hydrophobic pigments of high molecular weight (54, 88,
95, 139) that are composed of polymerized phenolic and/or indolic compounds (Fig. 1)(45 …
95, 139) that are composed of polymerized phenolic and/or indolic compounds (Fig. 1)(45 …
Melanin and fungi
BL Gómez, JD Nosanchuk - Current opinion in infectious diseases, 2003 - journals.lww.com
Melanin has been referred to as 'fungal armor'due to the ability of the polymer to protect
microorganisms against a broad range of toxic insults. Recent publications continue to …
microorganisms against a broad range of toxic insults. Recent publications continue to …