Despite continuing advances in the development of biomacromolecules for therapeutic
purposes, successful application of these often large and hydrophilic molecules has been …

Abstracts Cell-penetrating peptides (CPPs), also known as protein transduction domains,
are a class of diverse amino acid sequences with the ability to cross cellular membranes …

Highlights•CPPs are valuable tools for the intracellular delivery of anti-cancer
drugs.•Attachment of targeting units to CPPs helps to increase their selectivity.•Self …

Cell penetrating peptides (CPPs) are 9-35mer cationic and/or amphipathic peptides that are
rapidly internalized across cell membranes. Importantly, they can be linked to a variety of …

Cell-penetrating peptides (CPP) provide an efficient strategy for the intracellular delivery of
bioactive molecules in various biomedical applications. This review focuses on recent …

Targeted delivery of cancer therapeutics and imaging agents aims to enhance the
accumulation of these molecules in a solid tumor while avoiding uptake in healthy tissues …

Introduction: Delivery of macromolecular drugs is an important field in medical research.
However, macromolecules are usually unable to cross the cell membrane without the …

Efficient intracellular trafficking and targeted delivery to the site of action are essential to
overcome the current drawbacks of cancer therapeutics. Cell Penetrating Peptides (CPPs) …

Simple Summary Crossing biological barriers is often required for drug delivery. Cell-
penetrating peptides (CPPs) are short strands of amino acids that have been widely used as …

Efficient delivery of therapeutic and diagnostic molecules to the cells and tissues is a difficult
challenge. The cellular membrane is very effective in its role as a selectively permeable …