Fungi are eukaryotic, single cell or multicellular organisms which cause a wide range of
human diseases ranging from superficial skin to invasive life-threatening infections. Over the …

Antifungals have always been considered as one of the astonishing discoveries of the 20th
century. This is correct, but the real marvel is the development of antifungal resistance in …

Antifungal agents constitute a major part of antiinfective drugs and have been in practice
since 16th century. Antifungal agents generally belong to the class of polyenes, azoles …

Due to their eukaryotic heritage, the differences between a fungal pathogen's molecular
makeup and its human host are small. Therefore, the discovery and subsequent …

Fungal infections are now becoming a hazard to individuals which has paved the way for
research to expand the therapeutic options available. Recent advances in drug design and …

Serious fungal infections, caused mostly by opportunistic species, are increasingly common
in immunocompromised and other vulnerable patients. The use of antifungal drugs, primarily …

In recent years, incidences of invasive fungal infections have greatly increased, especially in
immunosuppressed patients, but most today's antifungal drugs are not completely effective …

Invasive fungal infections remain a major cause of morbidity and mortality in
immunocompromised patients, and such infections are a substantial burden to healthcare …

Recent investigations have yielded both profound insights into the mechanisms required by
pathogenic fungi for virulence within the human host, as well as novel potential targets for …

Fungal infections represent an increasing threat to a growing number of immune-and
medically compromised patients. Fungi are eukaryotic organisms and, as such, there is a …