Using sensitivity analysis to develop a validated computational model of post-operative calvarial growth in sagittal craniosynostosis

C Cross, RH Khonsari, L Galiay… - Frontiers in Cell and …, 2021 - frontiersin.org
Craniosynostosis is the premature fusion of one or more sutures across the calvaria,
resulting in morphological and health complications that require invasive corrective surgery …

Predicting and comparing three corrective techniques for sagittal craniosynostosis

C Cross, RH Khonsari, D Larysz, D Johnson, L Kölby… - Scientific Reports, 2021 - nature.com
Sagittal synostosis is the most occurring form of craniosynostosis, resulting in calvarial
deformation and possible long-term neurocognitive deficits. Several surgical techniques …

Predicting calvarial morphology in sagittal craniosynostosis

O Malde, C Cross, CL Lim, A Marghoub… - Scientific Reports, 2020 - nature.com
Early fusion of the sagittal suture is a clinical condition called, sagittal craniosynostosis.
Calvarial reconstruction is the most common treatment option for this condition with a range …

A computational framework to predict calvarial growth: optimising management of sagittal craniosynostosis

C Cross, RH Khonsari, G Patermoster… - … in Bioengineering and …, 2022 - frontiersin.org
The neonate skull consists of several bony plates, connected by fibrous soft tissue called
sutures. Premature fusion of sutures is a medical condition known as craniosynostosis …

A population-specific material model for sagittal craniosynostosis to predict surgical shape outcomes

A Borghi, N Rodriguez Florez, F Ruggiero… - … and modeling in …, 2020 - Springer
Sagittal craniosynostosis consists of premature fusion (ossification) of the sagittal suture
during infancy, resulting in head deformity and brain growth restriction. Spring-assisted …

An overview of modelling craniosynostosis using the finite element method

O Malde, J Libby, M Moazen - Molecular syndromology, 2019 - karger.com
Craniosynostosis is a medical condition caused by the early fusion of the cranial joint. The
finite element method (FEM) is a computational technique that can answer a variety of “what …

Predicting calvarial growth in normal and craniosynostotic mice using a computational approach

A Marghoub, J Libby, C Babbs, E Pauws… - Journal of …, 2018 - Wiley Online Library
During postnatal calvarial growth the brain grows gradually and the overlying bones and
sutures accommodate that growth until the later juvenile stages. The whole process is …

Automated surgical planning in spring-assisted sagittal craniosynostosis correction using finite element analysis and machine learning

J Jacob, S Bozkurt - Plos one, 2023 - journals.plos.org
Sagittal synostosis is a condition caused by the fused sagittal suture and results in a
narrowed skull in infants. Spring-assisted cranioplasty is a correction technique used to …

Application of computer assisted three-dimensional simulation operation and biomechanics analysis in the treatment of sagittal craniosynostosis

X Li, W Zhu, J He, F Di, L Wang, X Li, W Liu, C Li… - Journal of Clinical …, 2017 - Elsevier
As a surgical method to treat children with sagittal craniosynostosis, calvarial vault
reconstruction is subjected to some limitations. In traditional surgical method to treat children …

Understanding the influence of surgical parameters on craniofacial surgery outcomes: a computational study

KH He, JL Bruse… - Royal Society …, 2024 - royalsocietypublishing.org
Sagittal craniosynostosis (SC) is a congenital condition whereby the newborn skull develops
abnormally owing to the premature ossification of the sagittal suture. Spring-assisted …