Identification of potential crucial genes associated with the pathogenesis and prognosis of liver hepatocellular carcinoma

L Shi, X Shang, K Nie, Z Lin, M Zheng… - Journal of clinical …, 2021 - jcp.bmj.com
Aims Liver hepatocellular carcinoma (LIHC) is the main manifestation of primary liver
cancer, with low survival rate and poor prognosis. Medical decision-making process of LIHC …

Identification of immune‐related prognostic mRNA and lncRNA in patients with hepatocellular carcinoma

D Chen, X Li, H Li, K Wang, X Tian - Journal of Oncology, 2022 - Wiley Online Library
Background. As the most common hepatic malignancy, hepatocellular carcinoma (HCC) has
a high incidence; therefore, in this paper, the immune‐related genes were sought as …

Integrated bioinformatics analyses of key genes involved in hepatocellular carcinoma immunosuppression

H Huang, Y Hu, L Guo, Z Wen - Oncology Letters, 2021 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is a typical inflammation‑driven cancer. Chronically
unresolved inflammation may remodel the immunosuppressive tumor microenvironment …

A Cell Cycle Progression‐Derived Gene Signature to Predict Prognosis and Therapeutic Response in Hepatocellular Carcinoma

Y Hui, J Leng, D Jin, D Liu, G Wang, Q Wang… - Disease …, 2021 - Wiley Online Library
Objective. Dysregulation of cell cycle progression (CCP) is one of the hallmarks of cancer.
Here, our study is aimed at developing a CCP‐derived gene signature for predicting high …

A Model of Basement Membrane‐Associated Gene Signature Predicts Liver Hepatocellular Carcinoma Response to Immune Checkpoint Inhibitors

J Shen, Z Wei, L Lv, J He, S Du, F Wang… - Mediators of …, 2023 - Wiley Online Library
Liver hepatocellular carcinoma (LIHC) is a highly lethal malignant tumor originating from the
digestive system, which is a serious threat to human health. In recent years, immunotherapy …

Seven chromatin regulators as immune cell infiltration characteristics, potential diagnostic biomarkers and drugs prediction in hepatocellular carcinoma

J Chai, X Hu, M Zhang, Y Dong - Scientific Reports, 2023 - nature.com
Abstract Treatment is challenging due to the heterogeneity of hepatocellular carcinoma
(HCC). Chromatin regulators (CRs) are important in epigenetics and are closely associated …

Model based on five tumour immune microenvironment-related genes for predicting hepatocellular carcinoma immunotherapy outcomes

X Gu, J Guan, J Xu, Q Zheng, C Chen, Q Yang… - Journal of translational …, 2021 - Springer
Background Although the tumour immune microenvironment is known to significantly
influence immunotherapy outcomes, its association with changes in gene expression …

Identifying tumor immunity-associated molecular features in liver hepatocellular carcinoma by multi-omics analysis

Q Shen, Y He, J Qian, X Wang - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
Background: Although current immunotherapies have achieved some successes for
hepatocellular carcinoma (HCC) patients, their benefits are limited for most HCC patients …

Exploring prognosis, tumor microenvironment and tumor immune infiltration in hepatocellular carcinoma based on ATF/CREB transcription factor family gene-related …

H Shen, X Gu, H Li, M Tang, X Li, Y Zhang… - Journal of …, 2023 - Taylor & Francis
Introduction Hepatocellular carcinoma (HCC) is the most common form of primary liver
cancer. It is the fourth leading cause of cancer-related death worldwide. Deregulation of the …

Single sample scoring of hepatocellular carcinoma: A study based on data mining

D Zhu, ZH Wu, L Xu, DL Yang - International Journal of …, 2021 - journals.sagepub.com
Hepatocellular carcinoma (HCC) is a high mortality malignancy and the second leading
cause of cancer-related deaths. Because the immune system plays a dual role by assisting …