Current knowledge on exosome biogenesis, cargo-sorting mechanism and therapeutic implications
S Xie, Q Zhang, L Jiang - Membranes, 2022 - mdpi.com
Extracellular vesicles (EVs) are nanoscale membrane vesicles released by donor cells that
can be taken up by recipient cells. The study of EVs has the potential to identify unknown …
can be taken up by recipient cells. The study of EVs has the potential to identify unknown …
Advances in exosome-based drug delivery and tumor targeting: from tissue distribution to intracellular fate
J Shao, J Zaro, Y Shen - International journal of nanomedicine, 2020 - Taylor & Francis
Exosomes or small extracellular vesicles are considered a new generation of bioinspired-
nanoscale drug delivery system (DDS). Endogenous exosomes function as signalosomes …
nanoscale drug delivery system (DDS). Endogenous exosomes function as signalosomes …
Post isolation modification of exosomes for nanomedicine applications
JL Hood - Nanomedicine, 2016 - Taylor & Francis
Exosomes are extracellular nanovesicles. They innately possess ideal structural and
biocompatible nanocarrier properties. Exosome components can be engineered at the …
biocompatible nanocarrier properties. Exosome components can be engineered at the …
Exosomes as drug carriers for cancer therapy
Exosomes, biological extracellular vesicles, have recently begun to find use in targeted drug
delivery in solid tumor research. Ranging from 30–120 nm in size, exosomes are secreted …
delivery in solid tumor research. Ranging from 30–120 nm in size, exosomes are secreted …
Exosome: a significant nano-scale drug delivery carrier
H Peng, W Ji, R Zhao, J Yang, Z Lu, Y Li… - Journal of Materials …, 2020 - pubs.rsc.org
In recent years, due to the limitations of the nature of therapeutic agents, many synthetic
nano-delivery systems have emerged to enhance the efficacy of drugs. Extracellular vesicles …
nano-delivery systems have emerged to enhance the efficacy of drugs. Extracellular vesicles …
Biodistribution of exosomes and engineering strategies for targeted delivery of therapeutic exosomes
H Choi, Y Choi, HY Yim, A Mirzaaghasi, JK Yoo… - Tissue engineering and …, 2021 - Springer
Exosomes are cell-secreted nano-sized vesicles which deliver diverse biological molecules
for intercellular communication. Due to their therapeutic potential, exosomes have been …
for intercellular communication. Due to their therapeutic potential, exosomes have been …
Engineering exosomes for cancer therapy
KE Gilligan, RM Dwyer - International journal of molecular sciences, 2017 - mdpi.com
There remains an urgent need for novel therapeutic strategies to treat metastatic cancer,
which results in over 8 million deaths annually worldwide. Following secretion, exosomes …
which results in over 8 million deaths annually worldwide. Following secretion, exosomes …
Exosomes as natural nanocarrier-based drug delivery system: recent insights and future perspectives
Abstract Exosomes are nanosized (size~ 30–150 nm) natural vesicular structures released
from cells by physiological processes or pathological circumstances. Exosomes are growing …
from cells by physiological processes or pathological circumstances. Exosomes are growing …
[HTML][HTML] New advances in exosome-based targeted drug delivery systems
D Ferreira, JN Moreira, LR Rodrigues - Critical Reviews in Oncology …, 2022 - Elsevier
In recent years, various drug nano-delivery platforms have emerged to enhance drug
effectiveness in cancer treatment. However, their successful translation to clinics have been …
effectiveness in cancer treatment. However, their successful translation to clinics have been …
Pharmacokinetics of exosomes—an important factor for elucidating the biological roles of exosomes and for the development of exosome-based therapeutics
M Morishita, Y Takahashi, M Nishikawa… - Journal of …, 2017 - Elsevier
Exosomes are small membrane vesicles containing lipids, proteins, and nucleic acids.
Recently, researchers have uncovered that exosomes are involved in various biological …
Recently, researchers have uncovered that exosomes are involved in various biological …