[HTML][HTML] Exosomes as drug carriers for cancer therapy and challenges regarding exosome uptake

X Zhao, D Wu, X Ma, J Wang, W Hou… - Biomedicine & …, 2020 - Elsevier
With the development of biomedicine, exosomes are rapidly developing as a new therapy
for tumors. As biological carriers, exosomes possess biological activity and can transport …

The therapeutic potential and clinical significance of exosomes as carriers of drug delivery system

T Li, X Li, G Han, M Liang, Z Yang, C Zhang, S Huang… - Pharmaceutics, 2022 - mdpi.com
Drug delivery system (DDS) realizes the drug delivery process through the drug carrier. As
an important part of DDS, the selection of the drug carrier material is extremely critical, which …

Unlocking the power of exosomes for crossing biological barriers in drug delivery

RO Elliott, M He - Pharmaceutics, 2021 - mdpi.com
Since the 2013 Nobel Prize was awarded for the discovery of vesicle trafficking, a subgroup
of nanovesicles called exosomes has been driving the research field to a new regime for …

Exploitation of exosomes as nanocarriers for gene-, chemo-, and immune-therapy of cancer

A Srivastava, A Babu, J Filant… - Journal of …, 2016 - ingentaconnect.com
The bottleneck in current vector-based cancer therapy is the targeted and controlled release
of therapeutics in tumors. Exosomes are submicron-sized vesicles that are secreted by all …

Exosomes and other extracellular vesicles with high therapeutic potential: their applications in oncology, neurology, and dermatology

U Szwedowicz, Z Łapińska, A Gajewska-Naryniecka… - Molecules, 2022 - mdpi.com
Until thirty years ago, it was believed that extracellular vesicles (EVs) were used to remove
unnecessary compounds from the cell. Today, we know about their enormous potential in …

Biomimetic exosomes: a new generation of drug delivery system

X Wang, X Zhao, Y Zhong, J Shen… - Frontiers in bioengineering …, 2022 - frontiersin.org
Most of the naked drugs, including small molecules, inorganic agents, and
biomacromolecule agents, cannot be used directly for disease treatment because of their …

Exosomal targeting and its potential clinical application

J He, W Ren, W Wang, W Han, L Jiang… - Drug Delivery and …, 2022 - Springer
Exosomes are extracellular vesicles secreted by a variety of living cells, which have a
certain degree of natural targeting as nano-carriers. Almost all exosomes released by cells …

Designer exosomes as next-generation cancer immunotherapy

BM Bell, ID Kirk, S Hiltbrunner, S Gabrielsson… - … , Biology and Medicine, 2016 - Elsevier
Exosomes are small 40-120 nm vesicles secreted by nearly all cells and are an important
form of intercellular communication. Exosomes are abundant, stable, and highly …

Emerging applications of exosomes in cancer therapeutics and diagnostics

S Inamdar, R Nitiyanandan… - … & translational medicine, 2017 - Wiley Online Library
Exosomes are nanoscale extracellular vesicles that are shed from different cells in the body.
Exosomes encapsulate several biomolecules including lipids, proteins, and nucleic acids …

Organically derived exosomes as carriers of anticancer drugs and imaging agents for cancer treatment

A Srivastava, S Rathore, A Munshi… - Seminars in cancer biology, 2022 - Elsevier
Extracellular vesicles (EVs), is the umbrella term used for different types of vesicles
produced by the cells, among which exosomes form the largest group. Exosomes perform …