Exosome-based drug delivery systems in cancer therapy

T Wang, Y Fu, S Sun, C Huang, Y Yi, J Wang… - Chinese Chemical …, 2023 - Elsevier
Exosome, which is a kind of extracellular vesicles with size around 40-160 nm, plays an
important role in cell-to-cell communication in multiple diseases. Especially in tumor …

Exosome biogenesis, bioactivities and functions as new delivery systems of natural compounds

AA Farooqi, NN Desai, MZ Qureshi… - Biotechnology …, 2018 - Elsevier
A rapidly growing body of experimental evidence has begun to shed light on the wide
ranging molecular mechanisms which modulate intra-and inter-cellular communications. A …

Advances in analysis of biodistribution of exosomes by molecular imaging

YW Yi, JH Lee, SY Kim, CG Pack, DH Ha… - International journal of …, 2020 - mdpi.com
Exosomes are nano-sized membranous vesicles produced by nearly all types of cells. Since
exosome-like vesicles are produced in an evolutionarily conserved manner for information …

Exosome manufacturing status

W Whitford, P Guterstam - Future medicinal chemistry, 2019 - Taylor & Francis
Exosomes are secreted by mammalian cells and are widely distributed in cellular systems.
They are a medium of information and material transmission. The complexity of exosome …

Exosome-like nanovectors for drug delivery in cancer

N Arrighetti, C Corbo, M Evangelopoulos… - Current medicinal …, 2019 - ingentaconnect.com
Cancer treatment still represents a formidable challenge, despite substantial advancements
in available therapies being made over the past decade. One major issue is poor …

Exosome-based candidates move into the clinic

M Cully - Nat Rev Drug Discov, 2021 - nature.com
Nearly 50 years ago, scientists noticed that cells in culture 'exfoliated'small sacs of then
unknown function. Subsequent work has shown that these structures, now known as …

[HTML][HTML] Exosomes: Small vesicles with big roles in cancer, vaccine development, and therapeutics

A Thakur, DC Parra, P Motallebnejad, M Brocchi… - Bioactive materials, 2022 - Elsevier
Cancer is a deadly disease that is globally and consistently one of the leading causes of
mortality every year. Despite the availability of chemotherapy, radiotherapy, immunotherapy …

Bioinspired exosome-like therapeutics and delivery nanoplatforms

M Lu, Y Huang - Biomaterials, 2020 - Elsevier
Exosomes have emerged as appealing candidate therapeutic agents and delivery
nanoplatforms due to their endogenous features and unique biological properties. However …

Exosome engineering in cell therapy and drug delivery

S Sadeghi, FR Tehrani, S Tahmasebi, A Shafiee… - …, 2023 - Springer
Cell-derived exosomes have opened new horizons in modern therapy for advanced drug
delivery and therapeutic applications, due to their key features such as low immunogenicity …

Exosome-based cancer therapy: implication for targeting cancer stem cells

J Wang, Y Zheng, M Zhao - Frontiers in pharmacology, 2017 - frontiersin.org
Drug resistance, difficulty in specific targeting and self-renewal properties of cancer stem
cells (CSCs) all contribute to cancer treatment failure and relapse. CSCs have been …