Exosome-like systems: nanotechnology to overcome challenges for targeted cancer therapies
J García-Fernández, M de la Fuente Freire - Cancer Letters, 2023 - Elsevier
Exosomes are natural extracellular nanovesicles (30–150 nm in diameter) with the ability to
interact with and be taken up by specific cells. They are being explored as delivery systems …
interact with and be taken up by specific cells. They are being explored as delivery systems …
Exosomes as therapeutics: the implications of molecular composition and exosomal heterogeneity
SW Ferguson, J Nguyen - Journal of Controlled Release, 2016 - Elsevier
Harnessing exosomes as therapeutic drug delivery vehicles requires a better understanding
of exosomal composition and their mode of action. A full appreciation of all the exosomal …
of exosomal composition and their mode of action. A full appreciation of all the exosomal …
Exosomes: biogenesis, biologic function and clinical potential
Y Zhang, Y Liu, H Liu, WH Tang - Cell & bioscience, 2019 - Springer
Exosomes are nano-sized biovesicles released into surrounding body fluids upon fusion of
multivesicular bodies and the plasma membrane. They were shown to carry cell-specific …
multivesicular bodies and the plasma membrane. They were shown to carry cell-specific …
Functional exosome-mimic for delivery of siRNA to cancer: in vitro and in vivo evaluation
Exosomes, the smallest subgroup of extracellular vesicles, have been recognized as
extracellular organelles that contain genetic and proteomic information for long distance …
extracellular organelles that contain genetic and proteomic information for long distance …
Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER
W Heusermann, J Hean, D Trojer, E Steib… - Journal of Cell …, 2016 - rupress.org
Exosomes are nanovesicles released by virtually all cells, which act as intercellular
messengers by transfer of protein, lipid, and RNA cargo. Their quantitative efficiency, routes …
messengers by transfer of protein, lipid, and RNA cargo. Their quantitative efficiency, routes …
Exosome-based smart drug delivery tool for cancer theranostics
R Kar, R Dhar, S Mukherjee, S Nag… - ACS biomaterials …, 2023 - ACS Publications
Exosomes are the phospholipid-membrane-bound subpopulation of extracellular vesicles
derived from the plasma membrane. The main activity of exosomes is cellular …
derived from the plasma membrane. The main activity of exosomes is cellular …
Engineered exosomes from different sources for cancer-targeted therapy
M Zhang, S Hu, L Liu, P Dang, Y Liu, Z Sun… - Signal transduction and …, 2023 - nature.com
Exosome is a subgroup of extracellular vesicles, which has been serving as an efficient
therapeutic tool for various diseases. Engineered exosomes are the sort of exosomes …
therapeutic tool for various diseases. Engineered exosomes are the sort of exosomes …
[HTML][HTML] Tumor cell-derived exosomes home to their cells of origin and can be used as Trojan horses to deliver cancer drugs
Cancer is the second leading cause of death worldwide and patients are in urgent need of
therapies that can effectively target cancer with minimal off-target side effects. Exosomes are …
therapies that can effectively target cancer with minimal off-target side effects. Exosomes are …
The exosome journey: from biogenesis to uptake and intracellular signalling
S Gurung, D Perocheau, L Touramanidou… - Cell Communication and …, 2021 - Springer
The use of exosomes in clinical settings is progressively becoming a reality, as clinical trials
testing exosomes for diagnostic and therapeutic applications are generating remarkable …
testing exosomes for diagnostic and therapeutic applications are generating remarkable …
A systematic approach to exosome‐based translational nanomedicine
JL Hood, SA Wickline - Wiley Interdisciplinary Reviews …, 2012 - Wiley Online Library
Exosomes are a type of cell‐derived extracellular nanovesicle. They relay information
between cells. Some known exosome functions include immune modulation, promotion of …
between cells. Some known exosome functions include immune modulation, promotion of …