The MutS C terminus is essential for mismatch repair activity in vivo

MA Calmann, A Nowosielska… - Journal of bacteriology, 2005 - Am Soc Microbiol
An Escherichia coli K-12 strain was constructed with a chromosomal deletion (mutS Δ 800)
in the mutS gene that produced the removal of the C-terminal 53 amino acids which are not …

Dominant negative mutator mutations in the mutS gene of Escherichia coli

TH Wu, MG Marinus - Journal of bacteriology, 1994 - Am Soc Microbiol
The MutS protein of Escherichia coli is part of the dam-directed MutHLS mismatch repair
pathway which rectifies replication errors and which prevents recombination between …

Escherichia coli mutator mutD5 is defective in the mutHLS pathway of DNA mismatch repair.

RM Schaaper - Genetics, 1989 - academic.oup.com
We have previously reported that the Escherichia coli mutator strain mutD5 was defective in
the correction of bacteriophage M13mp2 heteroduplex DNA containing a TG mismatch …

Separation of mutation avoidance and antirecombination functions in an Escherichia coli mutS mutant

MA Calmann, A Nowosielska… - Nucleic acids …, 2005 - academic.oup.com
DNA mismatch repair in Escherichia coli has been shown to be involved in two distinct
processes: mutation avoidance, which removes potential mutations arising as replication …

Mutants with Temperature-Sensitive Defects in the Escherichia coli Mismatch Repair System: Sensitivity to Mispairs Generated In Vivo

ES Hong, A Yeung, P Funchain, MM Slupska… - Journal of …, 2005 - Am Soc Microbiol
We have used direct selections to generate large numbers of mutants of Escherichia coli
defective in the mismatch repair system and have screened these to identify mutants with …

Escherichia coli mutS-encoded protein binds to mismatched DNA base pairs.

SS Su, P Modrich - Proceedings of the National Academy of …, 1986 - National Acad Sciences
The Escherichia coli mutS gene product is involved in mismatch correction in this organism.
We have purified a biologically active form of the 97,000 Mr protein to near homogeneity …

The extreme mutator effect of Escherichia coli mutD5 results from saturation of mismatch repair by excessive DNA replication errors.

RM Schaaper, M Radman - The EMBO journal, 1989 - embopress.org
Escherichia coli mutator mutD5 is the most potent mutator known. The mutD5 mutation
resides in the dnaQ gene encoding the proofreading exonuclease of DNA polymerase III …

Nucleotide sequence of the Salmonella typhimurium mutS gene required for mismatch repair: homology of MutS and HexA of Streptococcus pneumoniae

LT Haber, PP Pang, DI Sobell, JA Mankovich… - Journal of …, 1988 - Am Soc Microbiol
The mutS gene product of Escherichia coli and Salmonella typhimurium is one of at least
four proteins required for methyl-directed mismatch repair in these organisms. A functionally …

Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteins.

RA Reenan, RD Kolodner - Genetics, 1992 - academic.oup.com
Homologs of the Escherichia coli (mutL, S and uvrD) and Streptococcus pneumoniae (hexA,
B) genes involved in mismatch repair are known in several distantly related organisms …

Deletion mutation analysis of the mutS gene inEscherichia coli

TH Wu, MG Marinus - Journal of Biological Chemistry, 1999 - ASBMB
The MutS protein is part of thedam-directed MutHLS mismatch repair pathway inEscherichia
coli. We have constructed deletion derivatives in the mutS gene, which retain the P-loop …