Presence of maternally-derived antibodies at time of immunization is known to often interfere
with active infant immunization, although with variable degrees of clinical significance. In …

The presence of maternally-derived antibodies at the time of immunization is known to
interfere frequently with active immunization, with variable levels of clinical significance …

Many serious infectious diseases occur early in life; efficacious vaccination of neonates has
been a longstanding goal in both human and veterinary medicine. Efforts to immunize in the …

The transfer of maternal antibodies to the offspring and their inhibitory effects on active infant
immunization is an important factor hampering the use of certain vaccines, such as measles …

Infants are born with immature immune systems, making it difficult for them to effectively
respond to the infectious pathogens encountered shortly after birth. Maternal antibody is …

During the last few decades, maternal immunization as a strategy to protect young infants
from infectious diseases has been increasingly recommended, yet some issues have …

Several mechanisms have been suggested as mediating the inhibitory influence of maternal
antibodies (MatAb) on infant responses. This inhibition is B cell determinant-specific …

Transplacentally-acquired antibodies are important for protection of infants in the early
months of life. Maternal antibodies may dampen the infant's primary antibody response to …

Neonates have an immature immune system, which cannot adequately protect against
infectious diseases. Early in life, immune protection is accomplished by maternal antibodies …

A potentially detrimental consequence of maternally transferred antibodies was
demonstrated in a mouse model for rabies virus, where pups from rabies virus-immune …