Dopaminergic mechanisms of individual differences in human effort-based decision-making
Preferences for different combinations of costs and benefits are a key source of variability in
economic decision-making. However, the neurochemical basis of individual differences in …
economic decision-making. However, the neurochemical basis of individual differences in …
The role of the striatum in effort-based decision-making in the absence of reward
Decision-making involves weighing costs against benefits, for instance, in terms of the effort
it takes to obtain a reward of a given magnitude. This evaluation process has been linked to …
it takes to obtain a reward of a given magnitude. This evaluation process has been linked to …
Neurocomputational mechanisms underlying subjective valuation of effort costs
In everyday life, we have to decide whether it is worth exerting effort to obtain rewards. Effort
can be experienced in different domains, with some tasks requiring significant cognitive …
can be experienced in different domains, with some tasks requiring significant cognitive …
Amping up effort: effects of d-amphetamine on human effort-based decision-making
Animal studies suggest the neurotransmitter dopamine (DA) plays an important role in
decision-making. In rats, DA depletion decreases tolerance for effort and probability costs …
decision-making. In rats, DA depletion decreases tolerance for effort and probability costs …
Dopamine, effort-based choice, and behavioral economics: basic and translational research
Operant behavior is not only regulated by factors related to the quality or quantity of
reinforcement, but also by the work requirements inherent in performing instrumental …
reinforcement, but also by the work requirements inherent in performing instrumental …
Calculating utility: preclinical evidence for cost–benefit analysis by mesolimbic dopamine
PEM Phillips, ME Walton, TC Jhou - Psychopharmacology, 2007 - Springer
Rationale Throughout our lives we constantly assess the costs and benefits of the possible
future outcomes of our actions and use this information to guide behavior. There is …
future outcomes of our actions and use this information to guide behavior. There is …
Motivational states influence effort-based decision making in rats: the role of dopamine in the nucleus accumbens
B Mai, S Sommer, W Hauber - Cognitive, Affective, & Behavioral …, 2012 - Springer
Decision-making policies are subject to modulation by changing motivational states.
However, so far, little is known about the neurochemical mechanisms that bridge …
However, so far, little is known about the neurochemical mechanisms that bridge …
Cortico-limbic-striatal circuits subserving different forms of cost-benefit decision making
SB Floresco, JRS Onge, S Ghods-Sharifi… - Cognitive, Affective, & …, 2008 - Springer
Research on the neural basis that underlies decision making in humans has revealed that
these processes are mediated by distributed neural networks that incorporate different …
these processes are mediated by distributed neural networks that incorporate different …
Effort-based decision making in the rat: an [18F] fluorodeoxyglucose micro positron emission tomography study
H Endepols, S Sommer, H Backes… - Journal of …, 2010 - Soc Neuroscience
Decision making refers to the process by which subjects choose between competing
courses of action based on the expected costs and benefits of their consequences. Lesion …
courses of action based on the expected costs and benefits of their consequences. Lesion …
Neural signatures of value comparison in human cingulate cortex during decisions requiring an effort-reward trade-off
MC Klein-Flügge, SW Kennerley, K Friston… - Journal of …, 2016 - Soc Neuroscience
Integrating costs and benefits is crucial for optimal decision-making. Although much is
known about decisions that involve outcome-related costs (eg, delay, risk), many of our …
known about decisions that involve outcome-related costs (eg, delay, risk), many of our …