Morphine analgesia, two-way avoidance, and consummatory behavior following lesions in the midbrain raphe nuclei of the rat

SA Lorens, LM Yunger - Pharmacology Biochemistry and Behavior, 1974 - Elsevier
Rats with lesions in the median raphe nucleus (MR group) or in both the dorsal and median
raphe nuclei (R group) were compared with operated control animals on the following …

Anxiolytic-like effects of median raphe nucleus lesion in the elevated T-maze

TGCS Andrade, CEA Macedo, H Zangrossi Jr… - Behavioural brain …, 2004 - Elsevier
The cell bodies of 5-HT containing neurons that innervate the limbic forebrain are mainly
found in the dorsal raphe nucleus and in the median raphe nucleus (MRN). To assess the …

Behavioral effects of selective midbrain raphe lesions in the rat

B Srebro, SA Lorens - Brain Research, 1975 - Elsevier
Lesions were produced in the median (n= 8), dorsal (n= 7) or both (n= 7) midbrain raphe
nuclei and their effects on behavior (days 16–54 postoperatively) compared to that of …

Effects of medial raphe and raphe magnus lesions on the analgesic activity of morphine and methadone

WT Chance, GM Krynock, JA Rosecrans - Psychopharmacology, 1978 - Springer
The effects of lesions of the raphe nuclei on opiate-induced antinociception and brain
serotonin (5-HT) levels were investigated. Lesions of the medial raphe nucleus effectively …

Raphe lesions in cats: forebrain serotonin avoidance behavior

SA Lorens - Pharmacology Biochemistry and Behavior, 1973 - Elsevier
Lesions in the central superior nucleus of Bechterew (also termed the median raphe
nucleus) in cats resulted in a 35% reduction in forebrain serotonin (5-HT) concentration and …

Differential behavioral effects of lesions of the medial or dorsal raphe nuclei in rats: Open field and pain-elicited aggression.

BL Jacobs, A Cohen - Journal of comparative and physiological …, 1976 - psycnet.apa.org
Electrolytic lesions were placed in either the dorsal or median raphe nuclei of 32 male adult
Sprague-Dawley rats. Both lesions produced significant reductions in forebrain serotonin …

Differential behavioral and neurochemical effects following lesions of the dorsal or median raphe nuclei in rats

BL Jacobs, WD Wise, KM Taylor - Brain research, 1974 - Elsevier
Locomotor activity and regional forebrain levels of serotonin (5-HT) were measured
following the placement of electrolytic lesions in either the dorsal or median raphe nucleus …

Evidence for regulation of water intake by median raphe serotonergic neurons

AL Barofsky, HC Grier, TK Pradhan - Physiology & behavior, 1980 - Elsevier
Radiofrequency lesions of the median raphe (MR) nucleus did not alter daily water intake in
the rat, whereas electrolytic lesions produced a transient polydipsia only during the first day …

Chemical lesions of both dorsal and median raphe nuclei and changes in social and aggressive behaviour in rats

SE File, JFW Deakin - Pharmacology Biochemistry and Behavior, 1980 - Elsevier
Abstract Microinjections of 5, 7-dihydroxytryptamine into both the dorsal and median raphe
nuclei resulted in 90% depletions of striatal and hippocampal 5-HT concentrations …

Increase of morphine-induced analgesia by stimulation of the nucleus raphe dorsalis

R Samanin, L Valzelli - European Journal of Pharmacology, 1971 - Elsevier
Doses of morphine, devoid of effect in the hot-plate or the tail electrical stimulation tests,
became analgesic if rats had been previously stimulated in the nucleus raphe dorsalis but …