Deleterious effects of neonicotinoid pesticides on Drosophila melanogaster immune pathways

JA Chmiel, BA Daisley, JP Burton, G Reid - MBio, 2019 - Am Soc Microbiol
Neonicotinoid insecticides are common agrochemicals that are used to kill pest insects and
improve crop yield. However, sublethal exposure can exert unintentional toxicity to honey …

Neonicotinoid-induced pathogen susceptibility is mitigated by Lactobacillus plantarum immune stimulation in a Drosophila melanogaster model

BA Daisley, M Trinder, TW McDowell, H Welle… - Scientific reports, 2017 - nature.com
Pesticides are used extensively in food production to maximize crop yields. However,
neonicotinoid insecticides exert unintentional toxicity to honey bees (Apis mellifera) that may …

Imbalance of intestinal microbial homeostasis caused by acetamiprid is detrimental to resistance to pathogenic bacteria in Bombyx mori

F Li, M Li, Q Zhu, T Mao, M Dai, W Ye, D Bian… - Environmental …, 2021 - Elsevier
Highlights•Sublethal doses of acetamiprid activated the Duox-ROS system and induced
ROS production.•Sublethal doses of acetamiprid dysregulated intestinal IMD immune …

Regulatory mechanisms of microbial homeostasis in insect gut

S Bai, Z Yao, MF Raza, Z Cai, H Zhang - Insect Science, 2021 - Wiley Online Library
Insects live in incredibly complex environments. The intestinal epithelium of insects is in
constant contact with microorganisms, some of which are beneficial and some harmful to the …

Imidacloprid decreases honey bee survival rates but does not affect the gut microbiome

K Raymann, EVS Motta, C Girard… - Applied and …, 2018 - Am Soc Microbiol
Accumulating evidence suggests that pesticides have played a role in the increased rate of
honey bee colony loss. One of the most commonly used pesticides in the United States is …

Decline in symbiont-dependent host detoxification metabolism contributes to increased insecticide susceptibility of insects under high temperature

Y Zhang, T Cai, Z Ren, Y Liu, M Yuan, Y Cai… - The ISME …, 2021 - academic.oup.com
The interactions between insects and their bacterial symbionts are shaped by a variety of
abiotic factors, including temperature. As global temperatures continue to break high …

Immune receptor signaling and the mushroom body mediate post-ingestion pathogen avoidance

JM Kobler, FJR Jimenez, I Petcu, ICG Kadow - Current Biology, 2020 - cell.com
In spite of the positive effects of bacteria on health, certain species are harmful, and
therefore, animals must weigh nutritional benefits against negative post-ingestion …

Entomopathogenic fungal-derived metabolites alter innate immunity and gut microbiota in the migratory locust

W Zhang, C Jia, LS Zang, M Gu, R Zhang… - Journal of Pest …, 2024 - Springer
There are complex temporal and spatial interactions between insects and microbes.
Previously, the function of microbial virulence factors has been identified and characterized …

[HTML][HTML] Ecotoxicological effects of common fungicides on the eastern honeybee Apis cerana cerana (Hymenoptera)

M Huang, J Dong, S Yang, M Xiao, H Guo… - Science of The Total …, 2023 - Elsevier
The widespread use of fungicides for plant protection has increased the potential for
pollinator exposure. This study therefore aimed at assessing the acute and chronic effects of …

Coordination of multiple dual oxidase–regulatory pathways in responses to commensal and infectious microbes in drosophila gut

EM Ha, KA Lee, YY Seo, SH Kim, JH Lim, BH Oh… - Nature …, 2009 - nature.com
All metazoan guts are in permanent contact with the microbial realm. However,
understanding of the exact mechanisms by which the strength of gut immune responses is …