Effects on specific promoter DNA methylation in zebrafish embryos and larvae following benzo [a] pyrene exposure
Abstract Benzo [a] pyrene (BaP) is an established carcinogen and reproductive and
developmental toxicant. BaP exposure in humans and animals has been linked to infertility …
developmental toxicant. BaP exposure in humans and animals has been linked to infertility …
Benzo [a] pyrene decreases global and gene specific DNA methylation during zebrafish development
DNA methylation is important for gene regulation and is vulnerable to early-life exposure to
environmental contaminants. We found that direct waterborne benzo [a] pyrene (BaP) …
environmental contaminants. We found that direct waterborne benzo [a] pyrene (BaP) …
Transcriptomic changes in zebrafish embryos and larvae following benzo [a] pyrene exposure
X Fang, J Corrales, C Thornton, T Clerk… - Toxicological …, 2015 - academic.oup.com
Abstract Benzo [a] pyrene (BaP) is an environmentally relevant carcinogenic and endocrine
disrupting compound that causes immediate, long-term, and multigenerational health …
disrupting compound that causes immediate, long-term, and multigenerational health …
Role of DNA methylation in altered gene expression patterns in adult zebrafish (Danio rerio) exposed to 3, 3', 4, 4', 5-pentachlorobiphenyl (PCB 126)
N Aluru, SI Karchner, KS Krick, W Zhu… - Environmental …, 2018 - academic.oup.com
There is growing evidence that environmental toxicants can affect various physiological
processes by altering DNA methylation patterns. However, very little is known about the …
processes by altering DNA methylation patterns. However, very little is known about the …
Global DNA methylation in gonads of adult zebrafish Danio rerio under bisphenol A exposure
Y Liu, Y Zhang, S Tao, Y Guan, T Zhang… - … and environmental safety, 2016 - Elsevier
Altered DNA methylation is pervasively associated with changes in gene expression and
signal transduction after exposure to a wide range of endocrine disrupting chemicals. As a …
signal transduction after exposure to a wide range of endocrine disrupting chemicals. As a …
Zebrafish embryos as a screen for DNA methylation modifications after compound exposure
MC Bouwmeester, S Ruiter, T Lommelaars… - Toxicology and applied …, 2016 - Elsevier
Modified epigenetic programming early in life is proposed to underlie the development of an
adverse adult phenotype, known as the Developmental Origins of Health and Disease …
adverse adult phenotype, known as the Developmental Origins of Health and Disease …
Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo [a] pyrene in zebrafish
Abstract Benzo [a] pyrene (B [a] P) is a well-known genotoxic polycylic aromatic compound
whose toxicity is dependent on signaling via the aryl hydrocarbon receptor (AHR). It is …
whose toxicity is dependent on signaling via the aryl hydrocarbon receptor (AHR). It is …
Bisphenol A causes reproductive toxicity, decreases dnmt1 transcription, and reduces global DNA methylation in breeding zebrafish (Danio rerio)
LV Laing, J Viana, EL Dempster, M Trznadel… - Epigenetics, 2016 - Taylor & Francis
Bisphenol A (BPA) is a commercially important high production chemical widely used in
epoxy resins and polycarbonate plastics, and is ubiquitous in the environment. Previous …
epoxy resins and polycarbonate plastics, and is ubiquitous in the environment. Previous …
Differential DNA methylation at conserved non-genic elements and evidence for transgenerational inheritance following developmental exposure to mono (2 …
Background Exposure to environmental stressors during development may lead to latent
and transgenerational adverse health effects. To understand the role of DNA methylation in …
and transgenerational adverse health effects. To understand the role of DNA methylation in …
Early-Life Benzo[a]Pyrene Exposure Causes Neurodegenerative Syndromes in Adult Zebrafish (Danio rerio) and the Mechanism Involved
D Gao, C Wang, Z Xi, Y Zhou, Y Wang… - Toxicological …, 2017 - academic.oup.com
There is increasing recognition of the importance of early-life environmental exposures in
health disorders at later-life stages. The aim of this study was to evaluate whether early-life …
health disorders at later-life stages. The aim of this study was to evaluate whether early-life …
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