Human RNA-binding protein HuR, a nucleocytoplasmic shuttling protein, is a ubiquitously
expressed member of the family of Hu proteins, which consist of two N-terminal RNA …

The messenger RNAs of many proto‐oncogenes, cytokines and lymphokines are targeted
for rapid degradation through AU‐rich elements (AREs) located in their 3′ untranslated …

The RNA-binding factor HuR is a ubiquitously expressed member of the Hu protein family
that binds and stabilizes mRNAs containing AU-rich elements (AREs). Hu proteins share a …

An important mechanism of posttranscriptional gene regulation in mammalian cells is the
rapid degradation of messenger RNAs (mRNAs) signaled by AU-rich elements (AREs) in …

AU-rich elements (AREs) control the expression of numerous genes by accelerating the
decay of their mRNAs. Rapid decay and deadenylation of β-globin mRNA containing AU …

Short lived cytokine and proto-oncogene mRNAs are destabilized by an A+ U-rich element
(ARE) in the 3′-untranslated region. Several regulatory proteins bind to AREs in cytokine …

In mammals, rapid mRNA turnover directed by AU-rich elements (AREs) is mediated by
selective association of cellular ARE-binding proteins. These trans-acting factors display …

The cationic amino acid transporter, Cat-1, is a high affinity transporter of the essential
amino acids, arginine and lysine. Expression of the cat-1 gene increases during nutritional …

Hu-antigen R (HuR) is a ubiquitous RNA-binding protein that comprises three RNA
recognition motifs (RRMs). The first two tandem RRMs are known to bind to AU-rich …

AU-rich elements (AREs) present in the 3′ untranslated regions of many protooncogene,
cytokine, and lymphokine messages target them for rapid degradation. HuR, a ubiquitously …