Transurethral surgery and twice-daily radiation plus paclitaxel-cisplatin or fluorouracil-cisplatin with selective bladder preservation and adjuvant chemotherapy for …

T Mitin, D Hunt, WU Shipley, DS Kaufman… - The lancet …, 2013 - thelancet.com
Background We assessed effectiveness, safety, and tolerability of paclitaxel or fluorouracil
when added to radiation plus cisplatin followed by adjuvant chemotherapy in a programme …

The initial results in muscle-invading bladder cancer of RTOG 95-06: phase I/II trial of transurethral surgery plus radiation therapy with concurrent cisplatin and 5 …

DS Kaufman, KA Winter, WU Shipley, NM Heney… - The …, 2000 - academic.oup.com
Purpose. To assess the safety, tolerance, and efficacy of transurethral surgery plus
concomitant cisplatin, 5-fluorouracil (5-FU), and radiation therapy in conjunction with …

Critical analysis of bladder sparing with trimodal therapy in muscle-invasive bladder cancer: a systematic review

G Ploussard, S Daneshmand, JA Efstathiou, HW Herr… - European urology, 2014 - Elsevier
Context Aims of bladder preservation in muscle-invasive bladder cancer (MIBC) are to offer
a quality-of-life advantage and avoid potential morbidity or mortality of radical cystectomy …

A phase I/II trial of transurethral surgery combined with concurrent cisplatin, 5-fluorouracil and twice daily radiation followed by selective bladder preservation in …

AL Zietman, WU Shipley, DS Kaufman, EM Zehr… - The Journal of …, 1998 - Elsevier
PURPOSE: We describe a protocol designed to evaluate the use of twice daily radiation
used together with cisplatin and 5 fluorouracil (5-FU) in the treatment of operable transitional …

Chemotherapy for muscle-invasive bladder cancer treated with definitive radiotherapy: persisting uncertainties

TK Choueiri, D Raghavan - Nature clinical practice Oncology, 2008 - nature.com
Radical cystectomy for invasive bladder cancer remains the standard of care in many parts
of the world, including North America and many parts of Europe; however, a large body of …

Phase I-II RTOG study (99-06) of patients with muscle-invasive bladder cancer undergoing transurethral surgery, paclitaxel, cisplatin, and twice-daily radiotherapy …

DS Kaufman, KA Winter, WU Shipley, NM Heney… - Urology, 2009 - Elsevier
OBJECTIVES: To evaluate the safety, tolerance, protocol completion rate, tumor response
rate, and patient survival of chemoradiotherapy for patients with muscle-invasive operable …

[HTML][HTML] Bladder preservation with twice-a-day radiation plus fluorouracil/cisplatin or once daily radiation plus gemcitabine for muscle-invasive bladder cancer: NRG …

JJ Coen, P Zhang, PJ Saylor, CT Lee… - Journal of Clinical …, 2019 - ncbi.nlm.nih.gov
Purpose Fluorouracil plus cisplatin and radiation twice a day (FCT) is an established
chemoradiation (CRT) regimen for selective bladder-sparing treatment of muscle-invasive …

A phase 1/2 trial of a combination of paclitaxel and trastuzumab with daily irradiation or paclitaxel alone with daily irradiation after transurethral surgery for …

MD Michaelson, C Hu, HT Pham, DM Dahl… - International Journal of …, 2017 - Elsevier
Purpose Bladder preservation therapy is an effective treatment for muscle-invasive urothelial
carcinoma (UC). In this study we treated noncystectomy candidates with daily radiation and …

Combined modality treatment with bladder preservation for muscle invasive bladder cancer

MA Sabaa, OM El-Gamal, M Abo-Elenen… - … Oncology: Seminars and …, 2010 - Elsevier
OBJECTIVE: To evaluate the 5-year results of the following trimodal therapy for treatment of
some selected cases of muscle invasive bladder cancer. MATERIALS AND METHODS: In …

Outcomes in patients with muscle-invasive bladder cancer treated with neoadjuvant chemotherapy followed by (chemo) radiotherapy in the BC2001 trial

SA Hussain, N Porta, E Hall, A Salawu, R Lewis… - European Urology, 2021 - Elsevier
Background BC2001 demonstrated improved local control with the addition of
chemotherapy to radiotherapy in 360 patients with muscle-invasive bladder cancer …