Imaging is an indispensable tool for brain tumour diagnosis, surgical planning, and follow-
up. Definite diagnosis, however, often demands histopathological analysis of microscopic …

Diagnosis of brain disorders is hindered by the lack of an imaging technique that reveals the
architecture of neuronal tissue at the cellular level, where the associated pathological …

Extracting microanatomical information beyond the image resolution of MRI would provide
valuable tools for diagnostics and neuroscientific research. A number of mathematical …

Diffusion MRI is a non-invasive technique to study brain microstructure. Differences in the
microstructural properties of tissue, including size and anisotropy, can be represented in the …

Abstract Background Monte Carlo simulations of diffusion are commonly used as a model
validation tool as they are especially suitable for generating the diffusion MRI signal in …

Diffusion MRI uses the random displacement of water molecules to sensitize the signal to
brain microstructure and to properties such as the density and shape of cells. Microstructure …

The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25
years. In this review, we dwell on the various challenges along the journey of bringing a …

This review discusses ex vivo diffusion magnetic resonance imaging (dMRI) as an important
research tool for neuroanatomical investigations and the validation of in vivo dMRI …

Non-invasive estimation of brain microstructure features using diffusion MRI (dMRI)—known
as Microstructure Imaging—has become an increasingly diverse and complicated field over …

In diffusion MRI analysis, advances in biophysical multi-compartment modeling have gained
popularity over the conventional Diffusion Tensor Imaging (DTI), because they can obtain a …