Immunogenetic factors in beryllium sensitization and chronic beryllium disease
A Weston, J Snyder, EC McCanlies, CR Schuler… - Mutation Research …, 2005 - Elsevier
Exposure to beryllium in the workplace can cause beryllium sensitization and chronic
beryllium disease. Sensitization to beryllium can be detected in the laboratory using the …
beryllium disease. Sensitization to beryllium can be detected in the laboratory using the …
Beryllium sensitivity is linked to HLA-DP genotype
Chronic beryllium disease (CBD) appears to arise from a combination of both exposure and
genetic risk factors. A distinguishing feature of CBD is beryllium hypersensitivity, which can …
genetic risk factors. A distinguishing feature of CBD is beryllium hypersensitivity, which can …
Genetic susceptibility and immune-mediated destruction in beryllium-induced disease
AP Fontenot, LA Maier - Trends in immunology, 2005 - cell.com
Chronic beryllium disease (CBD) is a hypersensitivity disorder caused by beryllium
exposure in the workplace and is characterized by the accumulation of beryllium-specific …
exposure in the workplace and is characterized by the accumulation of beryllium-specific …
Chronic beryllium disease, HLA-DPB1, and the DP peptide binding groove
LJ Silveira, EC McCanlies, TE Fingerlin… - The Journal of …, 2012 - journals.aai.org
Multiple epidemiologic studies demonstrate associations between chronic beryllium disease
(CBD), beryllium sensitization (BeS), and HLA-DPB1 alleles with a glutamic acid residue at …
(CBD), beryllium sensitization (BeS), and HLA-DPB1 alleles with a glutamic acid residue at …
Differential susceptibilities to chronic beryllium disease contributed by different Glu69 HLA-DPB1 and-DPA1 alleles
Z Wang, PS White, M Petrovic, OL Tatum… - The Journal of …, 1999 - journals.aai.org
Chronic beryllium disease (CBD) is associated with the allelic substitution of a Glu 69 in the
HLA-DPB1 gene. Although up to 97% of CBD patients may have the Glu 69 marker, about …
HLA-DPB1 gene. Although up to 97% of CBD patients may have the Glu 69 marker, about …
A genetic marker for chronic beryllium disease
C Saltini - Biomarkers and Occupational Health: Progress and …, 1995 - books.google.com
RESULTS With this background, we asked whether susceptibility to beryllium disease may
be associated with HLA allelic variants, namely with HLA-DP, which could be the best …
be associated with HLA allelic variants, namely with HLA-DP, which could be the best …
Beryllium presentation to CD4+ T cells underlies disease-susceptibility HLA-DP alleles in chronic beryllium disease
AP Fontenot, M Torres, WH Marshall… - Proceedings of the …, 2000 - National Acad Sciences
Chronic beryllium disease results from beryllium exposure in the workplace and is
characterized by CD4+ T cell-mediated inflammation in the lung. Susceptibility to this …
characterized by CD4+ T cell-mediated inflammation in the lung. Susceptibility to this …
HLA-DPB1 and Chronic Beryllium Disease: A HuGE Review
EC McCanlies, K Kreiss, M Andrew… - American Journal of …, 2003 - academic.oup.com
The human leukocyte antigen (HLA) complex is a series of genes located on chromosome 6
that are important in normal immune function. Susceptibility to chronic beryllium disease, a …
that are important in normal immune function. Susceptibility to chronic beryllium disease, a …
The association between HLA‐DPB1Glu69 and chronic beryllium disease and beryllium sensitization
EC McCanlies, JS Ensey, CR Schuler… - American journal of …, 2004 - Wiley Online Library
Background Several case‐control studies have found an association between chronic
beryllium disease (CBD) and HLA‐DPB1 gene variants. However, the relationship between …
beryllium disease (CBD) and HLA‐DPB1 gene variants. However, the relationship between …
Chronic beryllium disease: immune‐mediated destruction with implications for organ‐specific autoimmunity
AP Fontenot, BL Kotzin - Tissue Antigens, 2003 - Wiley Online Library
Chronic beryllium disease (CBD) is caused by exposure to beryllium in the workplace and is
characterized by an accumulation of beryllium‐specific CD4+ T cells with granulomatous …
characterized by an accumulation of beryllium‐specific CD4+ T cells with granulomatous …
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