Exposure to beryllium in the workplace can cause beryllium sensitization and chronic
beryllium disease. Sensitization to beryllium can be detected in the laboratory using the …

Chronic beryllium disease (CBD) appears to arise from a combination of both exposure and
genetic risk factors. A distinguishing feature of CBD is beryllium hypersensitivity, which can …

Chronic beryllium disease (CBD) is a hypersensitivity disorder caused by beryllium
exposure in the workplace and is characterized by the accumulation of beryllium-specific …

Multiple epidemiologic studies demonstrate associations between chronic beryllium disease
(CBD), beryllium sensitization (BeS), and HLA-DPB1 alleles with a glutamic acid residue at …

Chronic beryllium disease (CBD) is associated with the allelic substitution of a Glu 69 in the
HLA-DPB1 gene. Although up to 97% of CBD patients may have the Glu 69 marker, about …

RESULTS With this background, we asked whether susceptibility to beryllium disease may
be associated with HLA allelic variants, namely with HLA-DP, which could be the best …

Chronic beryllium disease results from beryllium exposure in the workplace and is
characterized by CD4+ T cell-mediated inflammation in the lung. Susceptibility to this …

The human leukocyte antigen (HLA) complex is a series of genes located on chromosome 6
that are important in normal immune function. Susceptibility to chronic beryllium disease, a …

Background Several case‐control studies have found an association between chronic
beryllium disease (CBD) and HLA‐DPB1 gene variants. However, the relationship between …

Chronic beryllium disease (CBD) is caused by exposure to beryllium in the workplace and is
characterized by an accumulation of beryllium‐specific CD4+ T cells with granulomatous …