For centuries, Malaria has continued to be one of the most deadly infectious diseases in the
world. Almost all of the current antimalarial drugs target the asexual blood stages of the …

Malaria remains one of the most prevalent and deadly infections across Asia, US and Africa.
The most lethal species causing malaria is Plasmodium falciparum. Malaria parasite has a …

Two quantitative nucleic acid sequence-based amplification assays (QT-NASBA) based on
Pfs16 and Pfs25, have been developed to quantify sexual stage commitment and mature …

Background The asexual blood stages of the human malaria parasite Plasmodium
falciparum produce highly immunogenic polymorphic antigens that are expressed on the …

Malaria elimination efforts would benefit from vaccines that block transmission of
Plasmodium falciparum gametocytes from humans to mosquitoes. A clear understanding of …

Immunity to the sexual stages of Plasmodium falciparum can be induced during natural
infections. Characterization of this immunity may facilitate the design of a transmission …

Malaria is the major cause of mortality and morbidity in tropical countries. The causative
agent, Plasmodium sp., has a complex life cycle and is armed with various mechanisms …

New strategies targeting Plasmodium falciparum gametocytes, the sexual-stage parasites
that are responsible for malaria transmission, are needed to eradicate this disease. Most …

Efforts to control malaria worldwide have led to significant progress in treating and
preventing malaria, yet over 228 million infections were reported in 2018. Each infection is a …