Background Pyrazinamide still may be a useful drug for treatment of rifampin-resistant (RR-
TB) or multidrug-resistant tuberculosis (MDR-TB) in China while awaiting scale up of new …

Background Pyrazinamide (PZA) plays a unique role in the treatment for multidrug-resistant
tuberculosis (MDR-TB) in both first-and second-line regimens. The aim of this study was to …

Purpose This study was designed to identify the phenotypic and genotypic characteristics of
pyrazinamide (PZA) resistance among multidrug-resistant Mycobacterium tuberculosis …

Objectives Pyrazinamide (PZA) is a crucial first-line tuberculosis (TB) drug recommended for
both drug-susceptible and multidrug-resistant Mycobacterium tuberculosis. This study aimed …

Background Detection of pyrazinamide (PZA) resistance in Mycobacterium tuberculosis (TB)
patients is critical, especially in dealing with multidrug-resistant Mycobacterium tuberculosis …

The technical limitations of common tests used for detecting pyrazinamide (PZA) resistance
in Mycobacterium tuberculosis isolates pose challenges for comprehensive and accurate …

Pyrazinamide (PZA) is an important first-line anti-tuberculosis drug, however, there are
relatively few available data on PZA resistant (PZA-R) rate in China. From June 2009 to …

Resistance to pyrazinamide (PZA) may impact clinical outcome of anti-tuberculosis
chemotherapy. PZA susceptibility testing using MGIT 960 is not reliable and little information …

Purpose Pyrazinamide (PZA) is a critical component of standardized chemotherapy for
tuberculosis (TB) and is recommended for the treatment of multidrug-resistant (MDR) TB. We …

Objective Pyrazinamide (PZA) is a cornerstone of modern tuberculosis regimens. This study
aimed to investigate the performance of genotypic testing of pncA+ upstream region, rpsA …