Acute kidney injury (AKI) is a common clinical problem and is associated with high mortality
rates. It is accepted that after AKI cellular regeneration of the proximal tubule occurs from …

Acute tubular injury accounts for the most common intrinsic cause for acute kidney injury.
Normally, the tubular epithelium is mitotically quiescent. However, upon injury, it can show a …

Acute kidney injury (AKI) is associated with high morbidity and mortality. Recent genetic fate
mapping studies demonstrated that recovery from AKI occurs from intrinsic tubular cells. It is …

The tubular compartment of the kidney is the primary site of a wide range of insults that can
result in acute kidney injury (AKI), a condition associated with high mortality and an …

The kidney possesses the capacity to repair after an acute insult, even one that causes
complete organ failure. This regenerative response is characterized by robust proliferation of …

Renal tubular epithelium has the capacity to regenerate, repair, and reepithelialize in
response to a variety of insults. Previous studies with several kidney injury models …

The kidney possesses profound regenerative potential and in some cases can recover
completely 'restitutio at integrum'following an acute kidney injury (AKI). Emerging evidence …

The kidney has a dramatic capacity to regenerate after injury. Whether stem cells are the
source of the epithelial progenitors replacing injured and dying tubular epithelium is …

Acute kidney injury (AKI), clinically defined by high serum creatinine and low urine flow, has
many complicated pathophysiological features including tubular and glomerular injury …

Understanding the mechanisms of nephron repair is critical for the design of new therapeutic
approaches to treat kidney disease. The kidney can repair after even a severe insult, but …