Preventing restenosis after implantation of bare stents with oral rapamycin: a randomized angiographic and intravascular ultrasound study with a 5-year clinical follow …

C Cernigliaro, M Sansa, G Vitrella, A Verde, AS Bongo… - Cardiology, 2009 - karger.com
Objectives: To establish the efficacy of oral rapamycin at a dose of 2 mg for 1 month at
reducing the 6-month restenosis rate after the implantation of bare metal stents. Methods: A …

Systemic rapamycin without loading dose for restenosis prevention after coronary bare metal stent implantation

S Stojkovic, M Ostojic, M Nedeljkovic… - Catheterization and …, 2010 - Wiley Online Library
Objectives: The aim of this study was to assess the role of short oral administration of
rapamycin, without loading dose, in the reduction of restenosis rate after bare metal stent …

Oral rapamycin after coronary bare-metal stent implantation to prevent restenosis: the Prospective, Randomized Oral Rapamycin in Argentina (ORAR II) Study

AE Rodriguez, JF Granada… - Journal of the American …, 2006 - jacc.org
Objectives: The purpose of this study was to assess the role of oral rapamycin in decreased
restenosis after bare metal stent implantation. Background: Small observational studies …

Oral rapamycin to prevent human coronary stent restenosis: a pilot study

E Guarda, E Marchant, A Fajuri, A Martínez… - American Heart …, 2004 - Elsevier
BACKGROUND: Recent human trials with rapamycin-eluting stents have shown very low
restenosis rates. However, the high costs of these devices preclude their use in routine …

Oral rapamycin to inhibit restenosis after stenting of de novo coronary lesions: the Oral Rapamune to Inhibit Restenosis (ORBIT) study

R Waksman, AE Ajani, AD Pichard, R Torguson… - Journal of the American …, 2004 - jacc.org
Objectives: The aim of this study was to establish safety and feasibility of oral Rapamycin at
two doses—2 mg and 5 mg—in achieving low rates of repeat target lesion revascularization …

Role of oral rapamycin to prevent restenosis in patients with de novo lesions undergoing coronary stenting: results of the Argentina single centre study (ORAR trial)

AE Rodríguez, MR Alemparte, CF Vigo, CF Pereira… - Heart, 2005 - heart.bmj.com
Objective: To assess the role of oral rapamycin in the prevention of coronary restenosis in
patients undergoing coronary stenting. Methods: From December 2001 through February …

[PDF][PDF] Pilot study of oral rapamycin to prevent restenosis in patients undergoing coronary stent therapy: Argentina Single-Center Study (ORAR Trial)

AE Rodríguez, MR Alemparte, CF Vigo, CF Pereira… - Age (years), 2003 - academia.edu
Rapamycin-coated stents are associated with low restenosis rates, but the ability of oral
rapamycin to prevent restenosis is unknown. From December 2001 through February 2002 …

Preliminary observations regarding angiographic pattern of restenosis after rapamycin-eluting stent implantation

A Colombo, D Orlic, G Stankovic, N Corvaja… - Circulation, 2003 - Am Heart Assoc
Background—Restenosis after implantation of drug-eluting stents (DES) is a rare
phenomenon, occurring more frequently peri-stent. Methods and Results—We evaluated the …

Does addition of estradiol improve the efficacy of a rapamycin-eluting stent? Results of the ISAR-PEACE randomized trial

T Adriaenssens, J Mehilli, R Wessely… - Journal of the American …, 2007 - jacc.org
Objectives: This study aimed to assess the efficacy of a rapamycin plus 17-β-estradiol–
eluting stent versus a rapamycin-eluting stent in patients with coronary artery disease …

Randomised trial of three rapamycin-eluting stents with different coating strategies for the reduction of coronary restenosis: 2-year follow-up results

RA Byrne, S Kufner, K Tiroch, S Massberg, KL Laugwitz… - Heart, 2009 - heart.bmj.com
Background: Drug-eluting stent (DES) platforms devoid of durable polymer have potential to
enhance long-term safety outcomes. The ISAR-TEST-3 study was a randomised trial …