Systematic review and meta-analysis of the magnitude of structural, clinical, and physician and patient barriers to cancer clinical trial participation

JM Unger, R Vaidya, DL Hershman… - JNCI: Journal of the …, 2019 - academic.oup.com
Background Barriers to cancer clinical trial participation have been the subject of frequent
study, but the rate of trial participation has not changed substantially over time. Studies often …

[HTML][HTML] Barriers to participation in clinical trials: a physician survey

A Mahmud, O Zalay, A Springer, K Arts… - Current …, 2018 - pmc.ncbi.nlm.nih.gov
Background Clinical trials are vital for evidence-based cancer care. Oncologist engagement
in clinical trials has an effect on patient recruitment, which in turn can affect trial success …

A systematic review highlights threats to validity in studies of barriers to cancer trial participation

D Fayter, C McDaid, A Eastwood - Journal of clinical epidemiology, 2007 - Elsevier
OBJECTIVE: To investigate the barriers, modifiers, and benefits involved in participating in
randomized controlled trials of cancer therapies as perceived by health care providers and …

“When offered to participate”: a systematic review and meta-analysis of patient agreement to participate in cancer clinical trials

JM Unger, DL Hershman, C Till… - JNCI: Journal of the …, 2021 - academic.oup.com
Background Patient participation in clinical trials is vital for knowledge advancement and
outcomes improvement. Few adult cancer patients participate in trials. Although patient …

[HTML][HTML] Role of clinical trial participation in cancer research: barriers, evidence, and strategies

JM Unger, E Cook, E Tai, A Bleyer - American Society of Clinical …, 2016 - ncbi.nlm.nih.gov
Fewer than 1 in 20 adult cancer patients enroll in cancer clinical trials. But although barriers
to trial participation have been the subject of frequent study, the rate of trial participation has …

Barriers to participation in therapeutic clinical trials as perceived by community oncologists

AR Wong, V Sun, K George, J Liu, S Padam… - JCO oncology …, 2020 - ascopubs.org
PURPOSE: Despite considerable research on the barriers to enrollment in cancer
therapeutic trials, few studies have elicited barriers from the perspective of community …

Association of patient comorbid conditions with cancer clinical trial participation

JM Unger, DL Hershman, ME Fleury, R Vaidya - JAMA oncology, 2019 - jamanetwork.com
Importance The American Society of Clinical Oncology (ASCO), Friends of Cancer
Research, and the US Food and Drug Administration recently recommended modernizing …

Barriers to clinical trial participation as perceived by oncologists and patients

NJ Meropol, JS Buzaglo, J Millard, N Damjanov… - Journal of the National …, 2007 - jnccn.org
Although clinical trial research is required for the development of improved treatment
strategies, very few cancer patients participate in these studies. The purpose of this study …

Overcoming barriers to clinical trial enrollment.

RD Nipp, K Hong, ED Paskett - American Society of Clinical …, 2019 - europepmc.org
Clinical trials are imperative for testing novel cancer therapies, advancing the science of
cancer care, and determining the best treatment strategies to enhance outcomes for patients …

Barriers to participation in clinical trials of cancer: a meta-analysis and systematic review of patient-reported factors

EJ Mills, D Seely, B Rachlis, L Griffith, P Wu… - The lancet …, 2006 - thelancet.com
Background Enrolling participants onto clinical trials of cancer presents an important
challenge. We aimed to identify the concerns of patients with cancer about, and the barriers …