Clostridioides difficile is a Gram-positive bacillus, which is a frequent cause of
gastrointestinal infections triggered by the depletion of the gut microbiome. Because of the …

Type IV pili are produced by many pathogenic Gram-negative bacteria and are important for
processes as diverse as twitching motility, biofilm formation, cellular adhesion, and …

Type IV pili are produced by many pathogenic Gram-negative bacteria and are important for
processes as diverse as twitching motility, cellular adhesion, and colonization. Recently …

The intestinal pathogen Clostridium difficile is an urgent public health threat that causes
antibiotic-associated diarrhea and is a leading cause of fatal nosocomial infections in the …

Increasing morbidity and mortality from Clostridium difficile infection (CDI) present an
enormous challenge to healthcare systems. Clostridium difficile express type IV pili (T4P) …

Abstract The Gram positive anaerobe Clostridium difficile is the major cause of nosocomial
diarrhea; manifestations of infection include diarrhea, pseudomembranous colitis, and …

Cyclic diguanylate (c-di-GMP) is a second messenger that regulates the transition from
motile to sessile lifestyles in numerous bacteria and controls virulence factor production in a …

Mucins are glycoproteins which can be found in host cell membranes and as a gelatinous
surface formed from secreted mucins. Mucosal surfaces in mammals form a barrier to …

Clostridium difficile is an opportunistic entero-pathogen causing post-antibiotic and
nosocomial diarrhea upon microbiota dysbiosis. Although biofilms could contribute to …

Clostridium difficile is an anaerobic Gram-positive bacterium that causes intestinal infections
with symptoms ranging from mild diarrhea to fulminant colitis. Cyclic diguanosine …