[HTML][HTML] Role of TLR4/MyD88/NF-κB signaling pathway in coronary microembolization-induced myocardial injury prevented and treated with nicorandil

Q Su, X Lv, Y Sun, Z Ye, B Kong, Z Qin - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Coronary microembolization (CME) is a common complication during the treatment of acute
coronary syndrome (ACS) and percutaneous coronary intervention (PCI). Nicorandil can be …

Nicorandil protects against coronary microembolization-induced myocardial injury by suppressing cardiomyocyte pyroptosis via the AMPK/TXNIP/NLRP3 signaling …

Y Liu, J Shu, T Liu, J Xie, T Li, H Li, L Li - European journal of pharmacology, 2022 - Elsevier
Background Coronary microembolization (CME) is a common and intractable complication
of coronary revascularization, which leads to perioperative myocardial injury, cardiac …

[HTML][HTML] Effects of nicorandil on PI3K/Akt signaling pathway and its anti-apoptotic mechanisms in coronary microembolization in rats

Q Su, L Li, J Zhao, Y Sun, H Yang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Coronary microembolization (CME) is a common complication of percutaneous coronary
intervention (PCI) for acute coronary syndrome. It leads to myocardial apoptosis and cardiac …

[HTML][HTML] Effects of the TLR4/Myd88/NF-κB signaling pathway on NLRP3 inflammasome in coronary microembolization-induced myocardial injury

Q Su, L Li, Y Sun, H Yang, Z Ye, J Zhao - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Coronary microembolization (CME) is a common complication of acute
coronary syndrome (ACS) and percutaneous coronary intervention (PCI); Myocardial …

TAK-242 protects against apoptosis in coronary microembolization-induced myocardial injury in rats by suppressing TLR4/NF-κB signaling pathway

X Wang, Y Lu, Y Sun, W He, J Liang, L Li - Cellular Physiology and …, 2017 - karger.com
Abstract Background/Aims: Myocardial apoptosis is heavily implicated in the myocardial
injury caused by coronary microembolization (CME), and toll-like receptor 4 (TLR4) is …

[HTML][HTML] Role of high mobility group A1/nuclear factor-kappa B signaling in coronary microembolization-induced myocardial injury

Q Su, X Lv, Y Sun, H Yang, Z Ye, L Li - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Objective Coronary microembolization (CME) is a common complication in percutaneous
coronary intervention (PCI). Local myocardial inflammation caused by CME is the major …

Beta blocker metoprolol protects against contractile dysfunction in rats after coronary microembolization by regulating expression of myocardial inflammatory cytokines

Y Lu, L Li, X Zhao, W Huang, W Wen - Life sciences, 2011 - Elsevier
Aims To examine the effects of metoprolol on expression of myocardial inflammatory
cytokines and myocardial function in rats following coronary microembolization (CME). Main …

The role of ERK1/2 signaling pathway in coronary microembolization-induced rat myocardial inflammation and injury

L Li, DH Li, N Qu, WM Wen, WQ Huang - Cardiology, 2011 - karger.com
Aim: Inflammation plays an important role in coronary microembolization (CME)-induced
myocardial injury. The present study was designed to investigate the role of extracellular …

The protective effect of nicorandil on cardiomyocyte apoptosis after coronary microembolization by activating Nrf2/HO-1 signaling pathway in rats

W He, Q Su, J Liang, Y Sun, X Wang, L Li - Biochemical and biophysical …, 2018 - Elsevier
Background Myocardial apoptosis is considered to be the chief cause of progressive cardiac
dysfunction induced by coronary microembolization (CME), and the Nrf2/HO-1 signaling …

Breviscapine pretreatment inhibits myocardial inflammation and apoptosis in rats after coronary microembolization by activating the PI3K/Akt/GSK-3β signaling …

ZQ Chen, Y Zhou, F Chen, JW Huang… - Drug design …, 2021 - Taylor & Francis
Purpose Coronary microembolization (CME) can cause myocardial inflammation, apoptosis
and progressive cardiac dysfunction. On the other hand, breviscapine exerts a significant …