Off-label dose direct oral anticoagulants and clinical outcomes in Asian patients with atrial fibrillation: a new evidence of Asian dose

W Xu, M Lv, T Wu, N Huang, W Zhang, J Su… - International Journal of …, 2023 - Elsevier
Aim This study aimed to evaluate the label compliance of DOACs in the Chinese AF
population and explore the relationship between inappropriate DOACs dosage and clinical …

Clinical outcomes of off-label dosing of direct oral anticoagulant therapy among Japanese patients with atrial fibrillation identified from the SAKURA AF Registry

N Murata, Y Okumura, K Yokoyama… - Circulation …, 2019 - jstage.jst.go.jp
Background: Off-label dosing of direct oral anticoagulants (DOACs) is encountered clinically
among patients with atrial fibrillation (AF), although data on the clinical outcomes of over …

[HTML][HTML] Effectiveness and safety of under or over-dosing of direct oral anticoagulants in atrial fibrillation: a systematic review and meta-analysis of 148909 patients …

NN Shen, C Zhang, N Wang, JL Wang… - Frontiers in …, 2021 - frontiersin.org
Background: In routine clinical practice, non-standard doses of direct oral anticoagulants
(DOACs) are commonly used in patients with atrial fibrillation (AF). However, data on the …

Effect of non‐recommended doses versus recommended doses of direct oral anticoagulants in atrial fibrillation patients: A meta‐analysis

X Liu, M Huang, C Ye, X Xiao, C Yan - Clinical Cardiology, 2021 - Wiley Online Library
Background Several observational studies have shown that the inappropriate dosing use of
direct oral anticoagulants (DOACs) in atrial fibrillation (AF) that does not conform to …

An Updated Pooled Analysis of Off-Label Under and Over-Dosed Direct Oral Anticoagulants in Patients with Atrial Fibrillation

NN Shen, E Ferroni, CB Amidei… - Clinical and Applied …, 2023 - journals.sagepub.com
Introduction Off-label, under-, and overdosed direct oral anticoagulants (DOACs) are
commonly prescribed to patients with atrial fibrillation (AF), but real-world evidence on their …

Effectiveness and Safety of Direct Oral Anticoagulants in Thai Patients with Atrial Fibrillation: A Real-World Retrospective Cohort Study

S Srikajornlarp, M Amnueypol… - Clinical and Applied …, 2022 - journals.sagepub.com
Background Direct oral anticoagulants (DOACs) are commonly used to prevent stroke and
systemic embolism in patients with atrial fibrillation (AF). However, studies into their …

Off-label under-and overdosing of direct oral anticoagulants in patients with atrial fibrillation: a meta-analysis

XL Zhang, XW Zhang, TY Wang, HW Wang… - … Quality and Outcomes, 2021 - Am Heart Assoc
Background: Prescriptions of off-label under-and overdosing of direct oral anticoagulants
(DOACs) are common for patients with atrial fibrillation, but their efficacy and safety remain …

Effectiveness and safety of off-label dose-reduced direct oral anticoagulants in atrial fibrillation

R Arbel, R Sergienko, A Hammerman… - The American Journal of …, 2019 - Elsevier
Abstract Background Direct oral anticoagulants (DOACs) reduce the risk of stroke and
systemic embolism in patients with nonvalvular atrial fibrillation but may result in serious …

Dose of direct oral anticoagulants and adverse outcomes in Asia

J Ohno, Y Sotomi, A Hirata, Y Sakata… - The American Journal of …, 2021 - Elsevier
The present study aimed to assess the associations between dosing of DOACs and
outcomes in patients with non-valvular atrial fibrillation (NVAF). Direct oral anticoagulants …

Effectiveness and safety of reduced and standard daily doses of direct oral anticoagulants in patients with nonvalvular atrial fibrillation: A cohort study using national …

K Kubota, N Ooba - Clinical Epidemiology, 2022 - Taylor & Francis
Purpose To compare the effectiveness and safety of reduced or standard daily doses of
direct oral anticoagulants (DOACs) with warfarin in Japanese patients with nonvalvular atrial …