Prostate cancer is a very common malignant disease and a leading cause of death for men
in the Western world. Tumorigenesis and progression of prostate cancer involves multiple …

Despite recent efforts, prostate cancer (PCa) remains one of the most common cancers in
men. Currently, there is no effective treatment for castration-resistant prostate cancer …

The Hippo signalling pathway is a master regulator of cell growth, proliferation, and cancer.
The transcriptional coregulators of the Hippo pathway, YAP and TAZ, are central in various …

Yes-associated protein (YAP) is an effector of the Hippo tumor suppressor pathway. The
functional significance of YAP in prostate cancer has remained elusive. In this study, we first …

Hippo signaling restricts tumor growth by inhibiting the oncogenic potential of YAP/TAZ‐
TEAD transcriptional complex. Here, we uncover a context‐dependent tumor suppressor …

Simple Summary Prostate cancer is the most commonly diagnosed cancer in men in the UK,
accounting for the deaths of over 11,000 men per year. A major problem in this disease are …

Objective: Yes associated protein 1 (YAP1) is a member of the Hippo pathway, acting as a
transcriptional coactivator. To elucidate the role of YAP1 and phosphorylated (p) YAP1 in …

Simple Summary YAP and TAZ are both transcriptional co-activators in the Hippo pathway.
New evidence reveals that they have unique and overlapping functions during tumor …

Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ)
are the major downstream effectors of the Hippo pathway, which regulates tissue …

Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ)
are two homologous transcriptional coactivators and the final effectors of the Hippo signaling …