Technology Insight: renal proteomics—at the crossroads between promise and problems

E O'riordan, SS Gross, MS Goligorsky - Nature Clinical Practice …, 2006 - nature.com
Abstract Knowledge of the human genome has fertilized research in the embryonic field of
proteomics. The aim of this Review is to examine the recent application of emerging …

Proteomic approaches in kidney disease biomarker discovery

Q Wu, RA Fenton - American Journal of Physiology-Renal …, 2018 - journals.physiology.org
Biomarkers have the potential to greatly facilitate diagnosis and treatment of patients with
various forms of kidney disease. State-of-the-art mass spectrometry-based methods possess …

Advances in urinary proteome analysis and biomarker discovery

D Fliser, J Novak, V Thongboonkerd… - Journal of the …, 2007 - journals.lww.com
Noninvasive diagnosis of kidney diseases and assessment of the prognosis are still
challenges in clinical nephrology. Definition of biomarkers on the basis of proteome …

Application of proteomic analysis to renal disease in the clinic

BA Julian, H Suzuki, G Spasovski… - PROTEOMICS …, 2009 - Wiley Online Library
Chronic kidney disease accounts for a significant portion of many national health‐care
budgets. In this viewpoint, we highlight recent advances in urinary proteomic analyses that …

Renal and urinary proteomics: current applications and challenges

V Thongboonkerd, P Malasit - Proteomics, 2005 - Wiley Online Library
During the past few years, proteomics has been extensively applied to various fields of
medicine including nephrology. Current applications of renal and urinary proteomics are to …

[HTML][HTML] Clinical proteomics: an insight into the urinary proteome

H Dihazi - Expert Review of Proteomics, 2006 - Taylor & Francis
One of the major difficulties facing nephrologists across the globe is the ever-increasing
number of patients suffering from chronic renal failure (and, eventually, end-stage renal …

The application of urinary proteomics for the detection of biomarkers of kidney diseases

S Jiang, Y Wang, Z Liu - Urine Proteomics in Kidney Disease Biomarker …, 2015 - Springer
Urine is a biological material that can be easily obtained in the clinic. The identification of
proteins excreted in urine provides useful biological information about the kidney as well as …

Proteomics and nephrology.

M Bonomini, V Sirolli, F Magni, A Urbani - Journal of nephrology, 2012 - europepmc.org
Proteome analysis has emerged as a new field of protein science offering the possibility of
achieving unbiased identification, quantification and functional assessment of all proteins …

The role of proteomics in the study of kidney diseases and in the development of diagnostic tools

U Christians, J Klawitter, J Klepacki - Biomarkers of kidney disease, 2017 - Elsevier
Proteins are the functional output of genes. The proteome is defined as the expressed
protein and peptide complement of a cell, organ, or organism, including all isoforms and …

Human kidney glomerulus proteome and biomarker discovery of kidney diseases

Y Yoshida, M Miyamoto, I Taguchi, B Xu… - PROTEOMICS …, 2008 - Wiley Online Library
The kidney glomerulus is the site of plasma filtration and production of primary urine in the
kidney. The structure not only plays a pivotal role in ultrafiltration of plasma into urine but …