[HTML][HTML] The impact of childhood obesity on skeletal health and development

P Dimitri - Journal of obesity & metabolic syndrome, 2019 - ncbi.nlm.nih.gov
Increased risk of fracture identified in obese children has led to a focus on the relationship
between fat, bone, and the impact of obesity during skeletal development. Early studies …

[HTML][HTML] Fat and bone in children–where are we now?

P Dimitri - Annals of pediatric endocrinology & metabolism, 2018 - ncbi.nlm.nih.gov
The risk of fracture secondary to low-impact trauma is greater in obese children, suggesting
obese children are at risk of skeletal fragility. However, despite this finding, there is a lack of …

The impact of fat and obesity on bone microarchitecture and strength in children

JN Farr, P Dimitri - Calcified tissue international, 2017 - Springer
A complex interplay of genetic, environmental, hormonal, and behavioral factors affect
skeletal development, several of which are associated with childhood fractures. Given the …

Fat and bone in children: differential effects of obesity on bone size and mass according to fracture history

P Dimitri, JK Wales, N Bishop - Journal of Bone and Mineral …, 2010 - academic.oup.com
Fat mass predicts bone accrual in prepubertal children, but obese children have increased
fracture risk. We hypothesised that bone size and mass would vary according to prior …

Obesity is not protective for bones in childhood and adolescence.

SJ Whiting - Nutrition reviews, 2002 - search.ebscohost.com
Abstract although body weight is considered to positively affect bones of children and adults,
recent studies suggest that overweight and obesity in childhood and adolescence reduce …

Adipose tissue stimulates bone growth in prepubertal children

EM Clark, AR Ness, JH Tobias… - The Journal of …, 2006 - academic.oup.com
Context: Fat mass represents a positive influence on bone mass in adults, independently of
other factors such as lean mass, but whether a similar action occurs in children is unclear …

Obesity is a risk factor for fracture in children but is protective against fracture in adults: a paradox

P Dimitri, N Bishop, JS Walsh, R Eastell - Bone, 2012 - Elsevier
With the rise in obesity worldwide, an important debate has developed as to whether excess
fat has a detrimental or protective effect on skeletal health in children and adults. Obese …

Body fat in children does not adversely influence bone development: a 7‐year longitudinal study (E arly B ird 18)

AJ Streeter, J Hosking, BS Metcalf, AN Jeffery… - Pediatric …, 2013 - Wiley Online Library
What is already known about this subject Both negative and positive associations have been
reported between body fat and bone density. Extra mechanical loading from excess fat may …

[HTML][HTML] Increased fat mass is associated with increased bone size but reduced volumetric density in pre pubertal children

ZA Cole, NC Harvey, M Kim, G Ntani, SM Robinson… - Bone, 2012 - Elsevier
Recent studies have shown that obesity is associated with an increased risk of fracture in
both adults and children. It has been suggested that, despite greater bone size, obese …

Childhood obesity as a risk factor for bone fracture: a mechanistic study

JE Kim, MH Hsieh, BK Soni, M Zayzafoon, DB Allison - Obesity, 2013 - Wiley Online Library
Objective To investigate the risk of bone fracture sustained by obese children exposed to
falls. The bone fracture risk of obese children would be greater than that of their nonobese …