Cholesterol homeostasis is essential for functional integrity of lipid. Niemann-Pick disease,
type C2 (NPC2) encodes a protein containing a lipid recognition domain. NPC2 is related to …

A relationship between cholesterol levels and Niemann-Pick C1-Like 1 (NPC1L1)
polymorphisms in diverse populations was found in previous studies. However, relevant …

Abstract Background The protein of Niemann-pick type C1 gene (NPC1) is known to
facilitate the egress of cholesterol and other lipids from late endosomes and lysosomes to …

Niemann–Pick type C1-like 1 (NPC1L1) protein is responsible for intestinal cholesterol
absorption. The aim of the study was to identify genetic polymorphisms of the NPC1L1 gene …

Objective—To study how Niemann-Pick disease type C1 (NPC1) influences hepatic
triacylglycerol (TG) metabolism and to determine whether this is reflected in circulating lipid …

The aim of the present study was to investigate the association between a genetic variation,
A+ 644G, in the Niemann‑Pick type C1 (NPC1) gene and the risk of cardiovascular disease …

Background Niemann-pick C1-like 1 (NPC1L1) is a key protein for intestinal cholesterol
transportation. Common single nucleotide polymorphisms (SNPs) in the NPC1L1 gene have …

Niemann–Pick type C1 (NPC1) disease is caused by defects in the NPC1 protein, which
result in perturbation of subcellular cholesterol transport. To identify related proteins that …

Some Shanghai Clinical Center fa role of Niemann-Pick type C1 (NPC1) for obesity traits.
However, whether the loss-of-function mutations in NPC1 cause adiposity in humans …

Abstract The Niemann-Pick C1 like 1 (NPC1L1) protein is a polytopic transmembrane
protein responsible for dietary cholesterol absorption. Genetic variation in the NPC1L1 gene …