This study aimed to identify the microRNAs associated with sclerotic status of subchondral
bone in the pathogenesis of osteoarthritis (OA). Total RNA was extracted from non-sclerotic …

Osteoarthritis (OA) is the most common degenerative disease affecting joint tissues. The
pathogenesis of OA is complex and poorly understood, as well as the multiple factors …

Osteoarthritis (OA) is a chronic disease and its etiology is complex. With increasing OA
incidence, more and more people are facing heavy financial and social burdens from the …

MicroRNAs are small non-coding RNA species with the ability to post-transcriptionally
control the expression of multiple genes, that have gained substantial interest because of …

OBJECTIVE: To identify differentially expressed microRNAs (miRNAs) in human
osteoarthritic (OA) cartilage and bone tissue and to determine their relevance to chondrocyte …

Micro ribonucleic acid (microRNA) regulation and expression has become an emerging field
in determining the mechanisms regulating a variety of inflammation-mediated diseases …

BACKGROUND: Expression profiles of microRNAs (miRNAs) can shape the repertoire of
proteins expressed in development, differentiation and diseases. This study aimed to identify …

MicroRNA (miRNA) is a class of noncoding RNA that exhibits tissue-or developmental stage-
specific expression patterns and negatively regulates gene expression. MiRNAs play an …

The abnormal expression of circulating miRNAs (c-miRNAs) has become an emerging field
in the development of miRNAs-based diagnostic and therapeutic tools for human diseases …

Osteoarthiritis (OA) is the most prevalent disease of articulating joints in human that
frequently results in joint pain, movement limitations, inflammation, and progressive …